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Question Answer Article
From which embyronic germ layer does the tunica muscularis develop?
  • Splanchnic mesoderm
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In development, how many degrees does the loop of gut rotate?
  • 270
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Where is the myenteric plexus?
  • Between the inner circular and outer longitudinal muscle layers of the tunica muscularis
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What are the functions of the small intestine?
  • Mixing, transportation, digestion and absorption
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Name the two types of muscle contraction in the small intestine.
  • Segemental and peristaltic
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What is the migrating myoelectric complex?
  • The peristaltic wave of contraction moves from the duodenum to the ileum
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What is the main structural difference between amylopectin and glycogen?
  • Both have α1-4 and α1-6 glycosidic bonds but glycogen has more α1-6 links, with shorter side chains
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What are the products of α-amylase digestion?
  • Di-, tri-, and oligo-saccharides
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Describe the mechanism of glucose absorption.
  • Na+/K+ pumps pump Na+ into the lumen. Na+ diffuses back into the enterocyte through a SGLT-1 symport which releases energy. Energy is used to transport glucose into the enterocyte up its concentration gradient.
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Which GLUT allows glucose to diffuse from the enterocyte to the blood?
  • GLUT 5
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Where does TAG digestion begin and with which enzyme?
  • Oral cavity with lingual lipase
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What are the functions of bile?
  • (i) emulsifies fat (ii) creates an interface for pancreatic lipase to digest water insoluble fat
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What positions can pancreatic lipase remove fatty acids from glycerol?
  • 1 and 3
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What is the rate limiting step in TAG digestion?
  • Isomerase reaction
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How do TAG leave the enterocyte?
  • In chylomicrons through lacteals into the lymph
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Where does protein digestion begin and with which enzyme?
  • Stomach, with pepsin
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Name three endopeptidases present in the small intestine.
  • Trypsin, chymotrypsin and elastase
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Where are carboxypeptidases produced?
  • In the pancreas, as zymogens
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How are di-, tri-, and oligo-peptides absorbed?
  • γ Glutamyl cycle
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Where effect does parasympathetic innervation have in the small intestine?
  • Increased motility and secretion
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Where are Brunner's glands located?
  • Submucosa of duodenum
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Name three cell types present in the muscosal crypts
  • (i)Goblet (ii)Entero-endocrine (iii) Paneth
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