Difference between revisions of "Systemic Lupus Erythematosus"

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==Treatment==
 
==Treatment==
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Treatment is with immunosuppressive drugs. Corticosteroids are the most widely used immunosuppresives, predinoslone or dexamethasone is used alone or in combination with azothioprine or cyclophosphamide in more sereve cases. Typically the dose can be tapered once the condtion is under control. 
  
 
==Prognosis==
 
==Prognosis==

Revision as of 11:50, 14 September 2010



Systemic Lupus Erythematosus is also known as SLE and Multi-systemic immune mediated disease

Description

Systemic Lupus Erythematous is an immune-mediated disease which can affect many different organ systems. The immune system is directed against various tissues of the body and immune complexes cause a type III hypersensitivity reaction. The condition is documented in cats and dogs but the etiology is not known. The disease has been reported in colonies of dogs suggesting that there may be a genetic or infectious component to the cause.

Signalment

Diagnosis

Clinical Signs

Treatment

Treatment is with immunosuppressive drugs. Corticosteroids are the most widely used immunosuppresives, predinoslone or dexamethasone is used alone or in combination with azothioprine or cyclophosphamide in more sereve cases. Typically the dose can be tapered once the condtion is under control.

Prognosis

References

Pathogenesis: Type III hypersensitivity