Difference between revisions of "Urea"

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Blood urea coentration may be elevated independently of creatinine for the following reasons:
 
Blood urea coentration may be elevated independently of creatinine for the following reasons:
*Gastro-intestinal haemorrhage, as with [[Gastric Ulcer - Dog|gastro-duodenal ulceration]].
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*Gastro-intestinal haemorrhage, as with [[Gastric Ulceration - Dog|gastro-duodenal ulceration]].
 
*Diet with high purine content, such as liver.
 
*Diet with high purine content, such as liver.
  

Revision as of 20:00, 23 July 2010



Also known as: Blood Urea Nitrogen - BUN
See also: Urea in lizards

Description

Urea is a form of nitrogenous waste formed from ammonia via the urea cycle in the liver. It freely crosses lipid membranes and is filtered into the glomerular filtrate in the renal glomerulus. A proportion of this filtered urea is reabsorbed passively before final excretion and it forms a vital of the concentration gradient needed to prevent passive diuresis.

Clinical Significance

An increase in serum concentrations of urea and creatinine is known as azotaemia and it is found almost exclusively in animals with kidney disease.

Blood urea coentration may be elevated independently of creatinine for the following reasons:

Reduced urea concentration: