B Cells flashcards - Anatomy & Physiology

Question	Answer	Article
Which type of dendritic cells present antigen to B cells?	Follicular dendritic cells	Link to Article
What are Russell bodies and in which type of B cell are they found?	Blobs of antibody in the cytoplasm Plasma cells	Link to Article
Where are plasma cells found?	Red pulp of the spleen Lymph node medulla Bone marrow	Link to Article
What is the process by which IgM, produced initially by plasma cells, can be converted into other immunoglobulins?	Class Switching	Link to Article
Which B cells remain in the cortex and proliferate to form germinal centres in lymph nodes?	Memory cells	Link to Article
Summarise the T cell independent response?	Activation of B cells by non-protinaceous antigen Does not require T cell help Produces IgM No difference between the first and subsequent responses	Link to Article
True or False: The primary T cell dependent response is quicker than the secondary response	False The secondary T cell dependent response is quicker than the primary response	Link to Article
Why is there a higher antibody titre in the secondary T cell dependent response?	Cloanal expansion occurs	Link to Article
True or False: There in no class switching but memory cells are produced in the T cell dependent response	False Class switching does occur Memory cells are produced	Link to Article

Originally funded by the RVC Jim Bee Award 2007