Calvarial Hyperostotic Syndrome
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- Idiopathic hyperostosis in calvaria of young male Bullmastiffs
- 5-10mths old, male
- Similar to craniomandibular osteopathy (CMO)
- Progressive and often assymetrical skull bone formation
- Grossly:
- Trabeceulae of the calvarial diploe are thickened and contiguous with a sunburst-like pattern of subperiosteal trabeculae composed of woven and lamellar bone
- Considerable remodeling (contrast with CMO – where there is rarely much remodeling of the woven bone to lamellar cortical bone)
- Histologically:
- Mild inflammation (mainly neutrophils)
- Loose fibrovascular connective tissue supporting stroma
- May be familial, ?sex linked