Clostridium perfringens type C
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- Acute enterotoxaemia in adult sheep, 'struck'
- Sudden death or terminal convulsions in sheep at pasture
- Beta toxin (lethal, necrotising) plays major role in pathogenesis of the disease - increases intestinal and capillary permeability
- Also alpha toxin (lecithinase)
- Post mortem: jejunal ulceration; hyperaemia in small intestine; fluid accumulation in peritoneal cavity; congestion of peritoneal vessels; petechial haemorrhages
- Haemorrhagic enteritis in piglets
- Peracute enterotoxaemia often of entire litter with mortality rates 80%
- Infection from sow's faeces
- Death within 24 hours in young piglets
- Chronic disease in older piglets
- Dullness, anorexia, bloody faeces, perianal hyperaemia
- Post mortem: necrosis of terminal small intestinal mucosa, caecum and colon and blood-stained contents; serosanguinous fluid in pleural and peritoneal cavities
- Necrotic enteritis in chickens:
- Broilers under 12 weeks
- Acute enterotoxaemia, sudden onset and high mortality
- Necrosis of small intestine
- Predisposing factors include diet changes, coccidial infection and intestinal hypomotility
- Acute enterotoxaemia with haemorrhagic enteritis in calves, lambs, foals, goats
- Peritonitis in cattle - sudden death in feedlot cattle