High Temperature Damage
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- May result from excessive heat, liquids, flames, friction, lightning, electricity
- Partial or full thickness burns (first, second and third degree burns)
- Full thickness burns:
- Total destruction of skin and adnexa
- Has to be repaired by grafting
- Life threatening
- Partial thickness burns:
- Some structures preserved -> regeneration may occur
- Grossly:
- Erythema (capillary dilation)
- Oedema (increased permeability of capillaries)
- Vesicles
- Microscopically:
- Coagulation necrosis of epidermis
- Subepidermal vesiculation
- Necrosis of adnexa
- Degenerated subepidermal collagen
- May involve large numbers of neutrophils if secondary ifection is present