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Created page with "[[Image:Hypertrophic osteodystrophy.jpg|right|thumb|100px|<small><center>Hypertrophic osteodystrophy (Image sourced from Bristol Biomed Image Archive with permission)</center></s..."
[[Image:Hypertrophic osteodystrophy.jpg|right|thumb|100px|<small><center>Hypertrophic osteodystrophy (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
*Also called - '''metaphyseal osteopathy'''
*Young (usually 3-6 months old), fast growing '''dogs''' of large or giant breeds
*'''Distal radius and ulna''' most severely affected
*Clinical signs:
**Fever
**Anorexia
**Severe lameness
**Swelling in '''metaphyses''' of long bones corresponding with neutrophilic infiltrate
*Radiologically:
**Increased lucency and increased density areas in metaphyses
**Enlarged metaphyses
*Usually bilaterally symmetrical
*Histologically:
**Haemorrhage and necrosis of [[Bones - Anatomy & Physiology|osteoblasts]] in the growth plates and primary spongiosa
**Intense infiltration by [[Neutrophils|neutrophils]]
**Periosteal reaction + formation of new bone on external surface above the lesion
*Many resolve spontaneously with complete remodelling and healing of the bone
*Can progress to '''periosteal bone proliferation'''
*Cause is unknown
**Unlikely to be dietary deficiency
**Likely to be infectious cause
*Contrast with [[Panosteitis|'''canine panosteitis''']]
[[Category:Bones - Hyperplastic Pathology]]
*Also called - '''metaphyseal osteopathy'''
*Young (usually 3-6 months old), fast growing '''dogs''' of large or giant breeds
*'''Distal radius and ulna''' most severely affected
*Clinical signs:
**Fever
**Anorexia
**Severe lameness
**Swelling in '''metaphyses''' of long bones corresponding with neutrophilic infiltrate
*Radiologically:
**Increased lucency and increased density areas in metaphyses
**Enlarged metaphyses
*Usually bilaterally symmetrical
*Histologically:
**Haemorrhage and necrosis of [[Bones - Anatomy & Physiology|osteoblasts]] in the growth plates and primary spongiosa
**Intense infiltration by [[Neutrophils|neutrophils]]
**Periosteal reaction + formation of new bone on external surface above the lesion
*Many resolve spontaneously with complete remodelling and healing of the bone
*Can progress to '''periosteal bone proliferation'''
*Cause is unknown
**Unlikely to be dietary deficiency
**Likely to be infectious cause
*Contrast with [[Panosteitis|'''canine panosteitis''']]
[[Category:Bones - Hyperplastic Pathology]]