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***Arise from bone marrow stroma
***Arise from bone marrow stroma
***Produce bone matrix = '''osteoid''' - uncalcified
***Produce bone matrix = '''osteoid''' - uncalcified
****Homogeneous substance
****Stains light pink with H&E
***Cell membranes are rich in alkaline phosphatase (ALP)
***Cell membranes are rich in alkaline phosphatase (ALP)
***Promoted by growth factors
***Promoted by growth factors