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Lymphoma (view source)

Revision as of 13:52, 15 August 2011

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[[File:Lymphoma in golden.JPG|right|thumb|200px| Lymphoma in a Golden Retriever (Wikimedia Commons)]]
 
[[File:Lymphoma in golden.JPG|right|thumb|200px| Lymphoma in a Golden Retriever (Wikimedia Commons)]]
 
Lymphoma is caused by malignant clonal expansion of lymphoid cells and most commonly arises from lymphoid tissues including the [[Bone Marrow|bone marrow]], [[Thymus - Anatomy & Physiology|thymus]], [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] and [[Spleen - Anatomy & Physiology|spleen]]. Lymphoma is documented to be the most common haematopoietic [[Neoplasia - Pathology|neoplasm]] in dogs.  
 
Lymphoma is caused by malignant clonal expansion of lymphoid cells and most commonly arises from lymphoid tissues including the [[Bone Marrow|bone marrow]], [[Thymus - Anatomy & Physiology|thymus]], [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] and [[Spleen - Anatomy & Physiology|spleen]]. Lymphoma is documented to be the most common haematopoietic [[Neoplasia - Pathology|neoplasm]] in dogs.  
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'''Classification'''
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:'''Cytological classification'''
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::Well differentiaed (lymphocytic) - The malignant cells represent normal lymphocytes, although in excessive numbers.
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::Poorly differentiated (lymphoblastic) - The malignant cells represent atypical lymphocytic cells with lymphoblastic characteristics.
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:'''Tumour distribution'''
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::Nodular/ follicular - A well organised pattern of slow growth, no metastasis, they are of the B-lymphocyte type
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::Diffuse - Result in effacement of normal lymphoid architecture by a very homogeneous population of lymphoid cells.
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:'''Anatomical classification'''
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::Thymic - Only the [[Thymus - Anatomy & Physiology|thymus]] is affected.
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::Alimentary - Gut and associated lymphoid tissue affected.
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::Multicentric - Widespread involvement of lymph nodes.
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::Cutaneous lymphoma - Usually presents as generalised skin disease, but is a malignant transformation of T cells with a propensity for  pithelial sites.
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:'''Type of lymphocyte''' - [[T-cell]], [[B-cel]] or [[NK-cell]]
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:'''Time scale''' - Acute or Chronic
    
===Dog===
 
===Dog===
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===== Classification=====
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* '''Cytological classification'''.
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** Well differentiaed (lymphocytic)
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*** The malignant cells represent normal lymphocytes, although in excessive numbers.
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** Poorly differentiated (lymphoblastic).
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*** The malignant cells represent atypical lymphocytic cells with lymphoblastic characteristics.
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* '''Tumour distribution'''
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** Nodular/ follicular.
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*** A well organised pattern of slow growth.
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*** No metastasis.
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*** Are of the B-lymphocyte type.
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** Diffuse.
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*** Result in effacement of normal lymphoid architecture by a very homogeneous population of lymphoid cells.
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* '''Anatomical classification'''
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** Thymic.
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** Only the [[Thymus - Anatomy & Physiology|thymus]].
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** Alimentary.
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*** Gut and associated lymphoid tissue.
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** Multicentric.
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*** Widespread involvement of lymph nodes.
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** Cutaneous lymphoma.
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*** Usually presents as generalised skin disease, but is a malignant transformation of T cells with a propensity for  pithelial sites
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* '''Type of lymphocyte'''
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** T-cell.
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** B-cell.
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** NK-cell.
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* '''Time scale'''
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** Acute.
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** Chronic.
      
=====Prevalence=====
 
=====Prevalence=====
Bara
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