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'''Substance P''' is involved in the transmission of pain from peripheral receptors to the central nervous system. It acts to increase the sensation, and therefore the conciousness, of pain and is released when [[Pain|nociceptors]] are activated. '''Enkaphalin''' acts to inhibit the release of substance P therefore acting to diminish the sensation of pain.
 
'''Substance P''' is involved in the transmission of pain from peripheral receptors to the central nervous system. It acts to increase the sensation, and therefore the conciousness, of pain and is released when [[Pain|nociceptors]] are activated. '''Enkaphalin''' acts to inhibit the release of substance P therefore acting to diminish the sensation of pain.
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'''Endorphin''' is part of a family of endogenous opioids which act as natural pain killers. They are produced by the pituitary gland and the hypothalamus and they chemically resemble opiates in their ability to produce analgesia and a sense of well-being. Endorphin has also been shown to stimulate dopaminergic neurones. In addition to this, endorphin can act to inhibit the release of '''substance P''' and therefore decrease the concious perception of pain.
 
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