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*Virulence varies with isolates
*Virulence varies with isolates
*Cessation of ciliary clearance and epithelial necrosis predisposes to secondary bacterial infections -> cough
*Cessation of ciliary clearance and epithelial necrosis predisposes to secondary bacterial infections -> cough
*With other agents causes [[Viral infections#Enzootic pneumonia of calves|calf pneumonia ]]
*May cause [[Viral infections#Parainfluenza- 3|rhinitis]] of cattle
*With other agents causes [[Bacterial infections#Enzootic pneumonia of calves|calf pneumonia ]]
**Together with managemental factors (overcrowding, poor ventilation, high humidity, deprivation of colostrum and stress caused by transport or mixing of stock)
**Together with managemental factors (overcrowding, poor ventilation, high humidity, deprivation of colostrum and stress caused by transport or mixing of stock)