Their removal from the site after the removal of infection is an important step in the resolution of the lesion. Under physiological conditions the neutrophils undergo a process called '''apoptosis''' (or ''Programmed Cell Death''), and are then cleared by tissue macrophages ([[#Macrophages|see above]]). However, if there are too few macrophages to clear the cells, or the infection is resulting in the death of the neutrophils, they undergo a process called '''necrosis'''. When these neutrophils that have undergone necrosis accumulate at the site of infection it forms '''pus'''.
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Their removal from the site after the removal of infection is an important step in the resolution of the lesion. Under physiological conditions the neutrophils undergo a process called '''apoptosis''' (or ''Programmed Cell Death''), and are then cleared by [[#Macrophages|tissue macrophages]] (see above). However, if there are too few macrophages to clear the cells, or the infection is resulting in the death of the neutrophils, they undergo a process called '''necrosis'''. When these neutrophils that have undergone necrosis accumulate at the site of infection it forms '''pus'''.