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301 bytes added ,  10:56, 9 February 2008
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***K88 (F4) is associated with adhesion to the small intestinal mucosa of pigs
 
***K88 (F4) is associated with adhesion to the small intestinal mucosa of pigs
 
***K99 (F5) associated with adhesion in pigs and cattle (these fimbrial adhesins were originally thought to be capsular (K) antigens)
 
***K99 (F5) associated with adhesion in pigs and cattle (these fimbrial adhesins were originally thought to be capsular (K) antigens)
***The fimbrae are encoded by plasmids
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***The fimbriae are encoded by plasmids
 
***These strains carry a plasmid which encodes an enterotoxin
 
***These strains carry a plasmid which encodes an enterotoxin
 
***Two types of enterotoxin: heat-labile (LT) and heat-stable (ST) toxins
 
***Two types of enterotoxin: heat-labile (LT) and heat-stable (ST) toxins
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**Possibly carried by cattle
 
**Possibly carried by cattle
 
**Produce shiga-like toxin, a vero toxin
 
**Produce shiga-like toxin, a vero toxin
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**Plasmid-coded fimbriae important for virulence
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**Intimin produced allowing intimate attchment to intestinal epithelial cells
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**Strains do not product LT or ST and are not enteroinvasive
 
**Attaching and effacing lesions, unrelated to toxin production
 
**Attaching and effacing lesions, unrelated to toxin production
 
**Disseminated intravascular coagulation and thrombus formation  
 
**Disseminated intravascular coagulation and thrombus formation  
 
**''E. coli'' O157:H7 causes haemorrhagic collitis-haemolytic uraemic syndrome in humans
 
**''E. coli'' O157:H7 causes haemorrhagic collitis-haemolytic uraemic syndrome in humans
 
*Cytotoxin necrotising factor-producing ''E. coli''
 
*Cytotoxin necrotising factor-producing ''E. coli''
**
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**Infrequently cause diarrhoea in calves, pigs and humans
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**Important virulence factors include toxin and fimbriae
     
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