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*Serological testing of milk (Milk Ring Test) and beef cattle (Rose Bengal Plate Test)
*Serological testing of milk (Milk Ring Test) and beef cattle (Rose Bengal Plate Test)
*Serological tests detect anti-lipopolysaccharide antibodies
*Serological tests detect anti-lipopolysaccharide antibodies
*LPS antigen present in virulent as well as some vaccine strains therefore vaccination may confuse serological testing
*False positives due to cross-reaction with LPS in other bacteria
*Vaccination:
**Strain S19, a live vaccine, stimulating a cell-mediated immune response; vaccination of young animals; interferes with serological testing
**Newer RB51 vaccine has no LPS O-antigen therefore not detcted by serological tests
**Live attenuated ''Brucella melitensis'' vaccine to protect sheep and goats against ''B. melitensis''
*Test and slaughter program has eradicated Brucellosis in the UK