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Neurogenesis - Anatomy & Physiology (view source)
Revision as of 15:02, 26 August 2008
, 15:02, 26 August 2008→Secondary Neuralation
#It is then made hollow by cavitations which join up to make a lumen.
#It is then made hollow by cavitations which join up to make a lumen.
*Tubes formed by primary and secondary neuralation fuse together to make one continuous tube called the neural tube.
*Tubes formed by primary and secondary neuralation fuse together to make one continuous tube called the neural tube.
==Neural Tube Development==
*The neural tube is one cell thick.
*The lumen of the neural tube enlarges as cells at the periphery of the lumen under mitosis.
*Cell division is governed by oscillations of the nucleus.
**When the nucleus reaches the luminal side of cell, the cell undergoes mitosis.
==Neural Tube Regionalisation==
*The neural tube undergoes regionalisation to define the anterior as the brain and posterior as the spinal cord.
*In the anterior, the neural tube swells into the three ventricles of the brain; forebrain; midbrain; and hindbrain.
**This occurs as fluid is pumped into the lumen of the neual tube.
**Pressure is regionalised to the anterior by occlusion of the neural tube at the base of the hindbrain. The occlusion reopens after enlargement of the ventricles.