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*Therefore, in lateral regions ectoderm becomes epidermis and along the midline ectoderm becomes neural ectoderm.
 
*Therefore, in lateral regions ectoderm becomes epidermis and along the midline ectoderm becomes neural ectoderm.
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==Primary Neuralation==
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==Neuralation==
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===Primary Neuralation===
    
#Cells of the neural plate proliferate causing the neural plate to thicken. Cells then converge at the midline and become wedge shaped, which drives the neural plate to become long and narrow.
 
#Cells of the neural plate proliferate causing the neural plate to thicken. Cells then converge at the midline and become wedge shaped, which drives the neural plate to become long and narrow.
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#*Failure of the neural tube to close causes '''spina bifida''' (spinal cord protrusion) and '''exencephaly''' (brain located out of the skull).
 
#*Failure of the neural tube to close causes '''spina bifida''' (spinal cord protrusion) and '''exencephaly''' (brain located out of the skull).
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==Secondary Neuralation==
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===Secondary Neuralation===
    
*Occurs posteriorly from the lumbar level onwards.
 
*Occurs posteriorly from the lumbar level onwards.
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