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Endocrine effects on the skin - Pathology (view source)
Revision as of 11:59, 29 October 2008
, 11:59, 29 October 2008→Specific changes associated with disease
**Castration may temporarily remove symptoms
**Castration may temporarily remove symptoms
*Superficial necrolytic dermatopathy
*'''Superficial necrolytic dermatopathy'''
**Also known as ''diabetic dermatopathy, hepatocutaneous syndrome''
**In older dogs with diabetes mellitus, hepatic dysfunction or pancreatic lesions
**Grossly: scaling and crusting, erythema, facial, genital and distal extremities alopecia, crusting, fissures and ulceration of foot pads
**Microscopically: trilaminar thickening of epidermis (outermost layer is keratotic, intermediate oedematous and vacuolated, inner is hyperplastic)