Changes

==Description==

==Description==

'''Lymphocytic cholangitis''' is a slowly progressive chronic disease characterised by infiltration of the portal areas of the liver with inflammatory cells, mostly lymphocytes and plasma cells.  Bile duct hypertrophy and fibrosis are present.  However, lymphocytic cholangitis does not progress to biliary cirrhosis.  An immune-mediated aetiology has been postulated but this has not been substantiated to date.  It is rarely associated with pancreatitis, compared to [[Neutrophilic Cholangitis]]

'''Lymphocytic cholangitis''' is a slowly progressive chronic disease characterised by infiltration of the portal areas of the liver with inflammatory cells, mostly [[Lymphocytes - WikiBlood|lymphocytes]] and [[B cell differentiation - WikiBlood#Plasma cells|plasma cells]].  Bile duct hypertrophy and [[Liver General Pathology - Pathology#Fibrosis - Repair|fibrosis]] are present.  However, lymphocytic cholangitis does not progress to biliary cirrhosis.  An immune-mediated aetiology has been postulated but this has not been substantiated to date.  It is rarely associated with pancreatitis, compared to [[Neutrophilic Cholangitis]]

 

==Diagnosis==

==Diagnosis==