Changes

Fungal infections are not uncommon in reptiles and can be the primary disease agent or secondary in already compromised individuals. Antifungal drugs may be useful but treatment regimens have not been established adequately.

Fungal infections are not uncommon in reptiles and can be the primary disease agent or secondary in already compromised individuals. Antifungal drugs may be useful but treatment regimens have not been established adequately.

Amphotericin- B

===Amphotericin-B===

Potentially nephrotoxic

*Potentially nephrotoxic

Can be used with ketaconazole

*Can be used with ketaconazole

Administer slowly

*Administer slowly

0.5 mg/kg IV q48-72h

*0.5 mg/kg IV q48-72h

5 mg/150ml saline x 1h nebulisation q12h 7d

*5 mg/150ml saline x 1h nebulisation q12h 7d

Fluconazole

===Fluconazole===

5 mg/kg PO q24h

*5 mg/kg PO q24h

Griseofulvin

===Griseofulvin===

Limited success

*Limited success

20-40 mg/kg PO q72h 5 Rxs

*20-40 mg/kg PO q72h 5 Rxs

Itraconazole

===Itraconazole===

Has been used in spiny lizards (Sceloporus spp.) at 23.5 mg/kg

*Has been used in spiny lizards (Sceloporus spp.) at 23.5 mg/kg

Ketaconazole

===Ketaconazole===

Potentially hepatotoxic

*Potentially hepatotoxic

15-30 mg/kg PO q24h 2-4w

*15-30 mg/kg PO q24h 2-4w

Nystatin

===Nystatin===

100,000 IU/kg PO q24h 2-4 w

*100,000 IU/kg PO q24h 2-4 w

==Antiparasitic==

==Antiparasitic==