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|<gallery>Image:Aspergillus in vivo.jpg|<center><p>'''Aspergillus in vivo'''</p>^{Copyright Professor Andrew N. Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath}</center></gallery>

|<gallery>Image:Aspergillus in vivo.jpg|<center><p>'''Aspergillus in vivo'''</p>^{Copyright Professor Andrew Rycroft, BSc, PHD, C. Biol.F.I.Biol., FRCPath}</center></gallery>

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==Diagnosis==

==Diagnosis==

In dogs, radiology is often peformed in the diagnostic work up of an animal with suspected Aspergillosis. Open-mouth ventro-dorsal views often reveal generalised radiolucency and lysis of the turbinate bones. Additionally, cytological examination of aspirates often reveals presence of fungal hyphae with granulomatous to suppurative inflammation and necrosis. Rhinoscopy may also be used to directly visualise the lesions, revealing characteristic white-green fungal plaques and destruction of the nasal turbinates. It also allows collection of material for fungal culture. This may be achieved using Sabouraud's dextrose agar in order to demonstrate the organism but should not be used as the sole means of diagnosis due to the ubiquitous nature of ''Aspergillus'' in the environment. White colonies form intitially which turn dark green, flat and velvet-like in appearance. Serological findings such as immunoelectophoresis, ELISA and agar gel diffusion may provide additional diagnostic information.

In dogs, radiology is often peformed in the diagnostic work up of an animal with suspected Aspergillosis. It should always be performed prior to other procedures such as rhinoscopy and biopsy in order to prevent haemorrhage that may obscure subtle radiographic findings. Open-mouth ventro-dorsal views often reveal generalised radiolucency and lysis of the turbinate bones. Additionally, cytological examination of aspirates often reveals presence of fungal hyphae with granulomatous to suppurative inflammation and necrosis. Rhinoscopy may also be used to directly visualise the lesions, revealing characteristic white-green fungal plaques and destruction of the nasal turbinates. It also allows collection of material for fungal culture. This may be achieved using Sabouraud's dextrose agar in order to demonstrate the organism but should not be used as the sole means of diagnosis due to the ubiquitous nature of ''Aspergillus'' in the environment. White colonies form intitially which turn dark green, flat and velvet-like in appearance. Serological findings such as immunoelectophoresis, ELISA and agar gel diffusion may provide additional diagnostic information.

In the horse, diagnosis is obtained following endoscopic examination of the guttural pouches and observation of white-yellow-black mycotic plaques on the mucosal surface of the guttural pouches. Care must be taken whilst performing endoscopy due to the risk of dislodgement of a thrombus on the affected artery.

In the horse, diagnosis is obtained following endoscopic examination of the guttural pouches and observation of white-yellow-black mycotic plaques on the mucosal surface of the guttural pouches. Care must be taken whilst performing endoscopy due to the risk of dislodgement of a thrombus on the affected artery.