Changes

{{unfinished}}

{{unfinished}}

==Description==

==Description==

'''Leptospirosis''' is a disease caused by the bacteria [[Leptospira|''Leptospira interrogans'']]. It affects domestic species, wildlife and has zoonotic potential. There are several different serovars which vary in pathogenesis and their host specificity. Most infections result in a self limiting pyrexia and anorexia, however occasionally the condition is more serious causing recurrent uveitis, abortion, or renal and hepatic disease. Recurrent uveitis is the most important clinical syndrome associated with Leptospirosis. The association has been well recognised for many years, originally thought to be an immune-mediated disease involving a cross reaction between antibodies against leptospira and ocular tissues. There is now additional evidence that live leptospira persist in the ocular fluids, providing continuous antigetic stimulation resulting in high antibodies titres in aqueous humour in comparison to the serum, suggesting that the eye is an immune privileged site.       

'''Leptospirosis''' is a disease caused by the bacteria [[Leptospira|''Leptospira interrogans'']]. It affects domestic species, wildlife and has zoonotic potential. There are several different serovars which vary in pathogenesis and their host specificity. Most infections result in a self limiting pyrexia and anorexia, however occasionally the condition is more serious causing '''recurrent uveitis''', '''abortion''', or renal and hepatic disease. Recurrent uveitis is the most important clinical syndrome associated with Leptospirosis. The association has been well recognised for many years, originally thought to be an immune-mediated disease involving a cross reaction between antibodies against leptospira and ocular tissues. There is now additional evidence that live leptospira persist in the ocular fluids, providing continuous antigetic stimulation resulting in high antibodies titres in aqueous humour in comparison to the serum, suggesting that the eye is an immune privileged site.       

==Signalment==

==Signalment==

Treatment should be directed towards the specific organ system affected.  

Treatment should be directed towards the specific organ system affected.  

Systemic antibiotics are indicated for pyrexic horses and those with acute renal failure. Appropriate antibiotics include [[Penicillins|pencillins]], [[Cephalosporins|cephalosporins]], enrofloxacin and  [[Tetracyclines|tetracyclines]]. IV fluid therapy is also warranted as supportive therapy in cases of acute renal failure.   

'''Systemic antibiotics''' are indicated for pyrexic horses and those with acute renal failure. Appropriate antibiotics include [[Penicillins|pencillins]], [[Cephalosporins|cephalosporins]], enrofloxacin and  [[Tetracyclines|tetracyclines]]. IV fluid therapy is also warranted as supportive therapy in cases of acute renal failure.   

[[Category:To_Do_-_lizzyk]]

[[Category:To_Do_-_lizzyk]]

[[Category:Reproductive Disorders - Horse]]

[[Category:Reproductive Disorders - Horse]]

[[Category:Zoonoses]]

[[Category:Zoonoses]]