Changes

====Phagocytosis====

====Phagocytosis====

Most bacteria are killed this way. [[Complement products]], bacterial components (e.g. f-Met-Leu-Phe) and locally released cytokines are chemotactic for phagocytes. The binding of the phagocyte can be mediated by the following:**Lectins on the bacteria, e.g. mannose-binding lectin of E. coli.

Most bacteria are killed this way. [[Complement|Complement products]], bacterial components (e.g. f-Met-Leu-Phe) and locally released cytokines are chemotactic for phagocytes. The binding of the phagocyte can be mediated by the following:

**Lectins on the bacteria, e.g. mannose-binding lectin of E. coli.

**Lectins on the phagocyte, e.g. complement receptors such as CR3.

**Lectins on the phagocyte, e.g. complement receptors such as CR3.

**[[Complement]] deposited on the organism, both classic and alternative pathways.

**[[Complement]] deposited on the organism, both classic and alternative pathways.

==Evading immune defences==[[Image:S aureus.jpg|thumb|right|100px|'''S. aureus''' Brian0918 2006, WikiMedia Commons]]

==Evading immune defences==

Bacteria can avoid the [[Complement|complement]] reponse. Proteins can be expressed on the surface that divert the lytic complex from the cell membrane; The outer membrane can resist the lytic complex; Some bacteria have an outer membrane that inhibits complement activation and An enzyme found on the membrane of some bacteria is able to degrade complement.

Bacteria can avoid the [[Complement|complement]] reponse. Proteins can be expressed on the surface that divert the lytic complex from the cell membrane; The outer membrane can resist the lytic complex; Some bacteria have an outer membrane that inhibits complement activation and An enzyme found on the membrane of some bacteria is able to degrade complement.