Changes

*Inactive kininogen (a 2-globulin fraction of plasma) is activated by plasmin and kallikreins which increases vascular permeability and leucocyte migration and may give rise to the pain sensation.

*Inactive kininogen (a 2-globulin fraction of plasma) is activated by plasmin and kallikreins which increases vascular permeability and leucocyte migration and may give rise to the pain sensation.

===The Complement System===

===The Complement System===

[[Complement|The complement system]] is another cascade system where inactive precursors in plasma are triggered by:  

The [[Complement|complement system]] is another cascade system where inactive precursors in plasma are triggered by:  

* Bacterial enzymes

* Bacterial enzymes

* Antigen-antibody complexes

* Antigen-antibody complexes