Changes

==Regulation of Coagulation==

==Regulation of Coagulation==

The blood coagulation process is beneficial, as it is designed to minimise blood loss, however, if the mechanism is prematurely or inadvertently triggered or fibrin deposition becomes excessive, the blood vessels may become obstructed. There is an inhibition system to guard against the  cascade being inappropriately triggered, and a mechanism to remove clots once their purpose has been achieved - ([[Haemostasis -  Pathology#Fibrinolysis|fibrinolysis]]). Normally there is a dynamic equilibrium between clotting and fibrinolysis so that the vascular system is guarded from the two principal hazards - [[Haemorrhage - Pathology|haemorrhage]] and excessive clotting.

The blood coagulation process is beneficial, as it is designed to minimise blood loss, however, if the mechanism is prematurely or inadvertently triggered or fibrin deposition becomes excessive, the blood vessels may become obstructed. There is an inhibition system to guard against the  cascade being inappropriately triggered, and a mechanism to remove clots once their purpose has been achieved - fibrinolysis. Normally there is a dynamic equilibrium between clotting and fibrinolysis so that the vascular system is guarded from the two principal hazards - [[Haemorrhage - Pathology|haemorrhage]] and excessive clotting.

===Natural Inhibitors===

===Natural Inhibitors===