5,582
edits
Changes
Jump to navigation
Jump to search
→Antigenicity
==Antigenicity==
==Antigenicity==
Viral subgroups have been categorised based on the different abnormalities detected in the host cellular envelope protein gp70. This protein interacts with a cellular receptor, and can prevent already infected cells from being targeted by further viral organisms.
There are 3 antigenic subgroups which are defined by the gp70 regulated viral response:
*Group A is transmitted between cats and is monotypic: one vaccine covers all isolates. Infection with this viral subgroup leads to '''lymphosarcoma'''.
*Group B is recombinant with transmissible FeLV-A; infection with viruses of this subgroup increases the chance of developing '''thymic tumors'''.
*Group C is a mutant of subgroup A. Isolates are rare, and occur as A+C mixtures, leading to an increased chance of developing '''anemia'''.
==Diagnosis==
==Diagnosis==