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Complement Associated Diseases (view source)
Revision as of 10:33, 6 September 2007
, 10:33, 6 September 2007→The binding of antibody to antigen
#** Forms C4b2¯b3b.
#** Forms C4b2¯b3b.
#*** This activates C5 and initiates the MAC.
#*** This activates C5 and initiates the MAC.
* Like the alternative pathway, another major effect of classical pathway activation is to produce iC3b.
* Like the alternative pathway, another major effect of classical pathway activation is to produce iC3b due to the actions of Factors I and H.
** Promotes phagocytosis and initiates inflammation.
** Promotes phagocytosis and initiates inflammation.
* All the Ca fragments (C2a, C3a, C4a, C5a) are chemotactic for neutrophils and induce of acute inflammation.
* All the Ca fragments (C2a, C3a, C4a, C5a) are chemotactic for neutrophils and induce of acute inflammation.