A Tribute to Nick Short
It is with extreme sadness that we share the news that one of WikiVet’s founders, Nick Short, has passed away.
Nick was the driving force behind WikiVet and all that it stood for, and it is thanks to his vision, innovative approach and tireless enthusiasm and belief, that WikiVet is available as a free resource to veterinary professionals around the world today. Nick’s dedication and passion for veterinary education were truly inspirational and his very many friends, colleagues and students across the world have lost a true gem. He was an exceptional human being: gentle, good-natured, charming, generous and kind: he has left many legacies which will ensure that he will be remembered for many years.
Our thoughts are with his friends and family at this heartbreaking time. A book of remembrance has been set up for anyone that would like to leave a message of condolence for Nick and his family have asked that anyone who wishes to do so make a donation to BipolarUK, a charity that was close to Nick’s heart.
Turkey Viral Hepatitis
|WikiVet LIVE - at the Virtual Congress 2021 - WikiVet has partnered with The Webinar Vet and created a student stream at the Virtual Congress 2021
There is a limited number of FREE tickets for students – on a first come first serve basis.
Also Known As: TVH — Turkey Hepatopancreatitis — Turkey Viral Hepatitis Virus — TVHV — THV
Turkey viral hepatitis (TVH) is caused by a virus of the family Picornaviridae but is at present not classified any further.
TVH is a highly contagious but generally subclinical disease.
TVH is reported in Canada, USA, Italy and the UK. Its distribution may be greater than this as monitoring is difficult due to the often subclinical nature of the disease.
Transmission is principally from faeces and can be direct or indirect. It is possible that vertical transmission also occurs.
TVH affects only turkeys (Meleagris gallopav). Disease occurs primarily in young, <6 weeks old birds.
When clinical disease does develop, it is characterised by anorexia, weight loss, depression and sudden deaths. As the hepatopathy develops, neurological signs may also develop.
Decreased hatchability and a drop in egg production are often also seen.
TVH is characterised by multifocal hepatic necrosis consisting of grey lesions that may be depressed and up to several mm in diameter +/- accompanying pancreatic necrosis at post-mortem. When present, pancreatic lesions are grey-pink and circular and can be very extensive. Vascular congestion and haemorrhage are often seen in fatal cases.
Microscopic changes are similar in both organs: vacuolation and mononuclear cell infiltrates are seen with bile duct proliferation. Blood often pools around areas of focal necrosis and necrotic cells are visible scattered among the leucocytes. Proliferating reticuloendothelial cells often form giant cells.
Virus isolation is the only other method of diagnosis. It can be achieved using liver, pancreas, spleen, kidney or faeces. Liver is preferred. Homogenised tissues or filtered faeces are inoculated into embryonated chicken eggs and observed for embryonic death and congestion or yolks are harvested. The virus can only be isolated from tissues and faeces until 28 days post infection.
Treatment and Control
No specific treatment or control measures are available. Minimisation of stress and faecal contamination may help.
|Turkey Viral Hepatitis Learning Resources|
Test your knowledge using flashcard type questions
|Turkey Viral Hepatitis Flashcards|
Gough, R.E. and McNulty, R.S. (2007) Picornaviridae. In: Poultry Diseases, 6th Edition (eds. Pattison, M., McMullin, P., Bradbury, J., Alexander, D.) Saunders, Elsevier, pp 350-358
Guy, J.S. (2008) Turkey Viral Hepatitis. In: Diseases of Poultry, 12th Edition (eds. Saif, Y.M., Fadly A.M., Glissen J.R., McDougald L.R., Nolan L.K., Swayne D.E.) Wiley-Blackwell, pp 426-430
The datasheet was accessed on 3 July 2011.
This article has been expert reviewed by Prof Dave Cavanagh BSc, PhD, DSc
Date reviewed: 23 August 2011
|WikiVet® Introduction - Help WikiVet - Report a Problem|