Difference between revisions of "Pancreatic Hypoplasia"

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*Tiny lobules with glandular cells, some appear to be undergoing regression, hence the alternative view that the [[Pancreas - Anatomy & Physiology|pancreas]] is normal at birth but undergoes progressive regression - [[Pancreatic Atrophy, Juvenile|juvenile atrophy]]
 
*Tiny lobules with glandular cells, some appear to be undergoing regression, hence the alternative view that the [[Pancreas - Anatomy & Physiology|pancreas]] is normal at birth but undergoes progressive regression - [[Pancreatic Atrophy, Juvenile|juvenile atrophy]]
 
*Hypoplastic parenchymal cells do not usually contain lipofuscin, which can be seen in atrophic cells
 
*Hypoplastic parenchymal cells do not usually contain lipofuscin, which can be seen in atrophic cells
[[Category:Pancreas - Developmental Pathology]][[Category:Alimentary Diseases - Cattle]][[Category:Pancreatic Diseases - Cat]][[Category:Pancreatic Diseases - Dog]]
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[[Category:Pancreas - Developmental Pathology]][[Category:Pancreatic Diseases - Cattle]][[Category:Pancreatic Diseases - Cat]][[Category:Pancreatic Diseases - Dog]]
 
[[Category:To_Do_-_Clinical]]
 
[[Category:To_Do_-_Clinical]]

Revision as of 16:50, 17 January 2011

Image of pancreatic hypoplasia in a dog from Cornell Veterinary Medicine

  • Occurs in calves, dogs (German Shepherd Dogs are the prevalent breed) and cats
  • Endocrine part of the pancreas seems unaffected

Clinical signs


Gross appearance

  • Pot-bellied appearance on external view
  • Intestines are distended by bulky fatty ingesta
  • Lack of fat in the mesentery and rest of the abdomen
  • The pancreas appears extremely thin and almost lace-like, is sparse and pink, easily visible due to lack of fat
  • The hypoplastic pancreas may be inconspicuous at laparotomy or post mortem examination owing to its small size


Microscopic appearance

  • Tiny lobules with glandular cells, some appear to be undergoing regression, hence the alternative view that the pancreas is normal at birth but undergoes progressive regression - juvenile atrophy
  • Hypoplastic parenchymal cells do not usually contain lipofuscin, which can be seen in atrophic cells