Difference between revisions of "Category:Intestine - Vascular Disturbances"

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* Vascular disturbances cause obstruction of efferent veins, blockage of afferent arteries or reduced blood flow through unobstructed circulation.
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** All have similar effects on the intestine
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Vascular disturbances cause obstruction of efferent veins, blockage of afferent arteries or reduced blood flow through unobstructed circulation. All have similar effects on the intestine.
  
 
'''Effects of Intestinal Hypoxia'''
 
'''Effects of Intestinal Hypoxia'''
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** 4 - 5 hours - all mucosa necrotic, sloughed.
 
** 4 - 5 hours - all mucosa necrotic, sloughed.
  
==[[Intestinal Venous Congestion]] ==
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==[[Intestinal Arterial Thromboembolism]] ==
 
  
* Non-strangulation infarction.
 
* There is often a functional obstruction at point of infarction.
 
* Relatively rare as the bowel has a good anastomosing blood supply.
 
[[Image:strongylus vulgaris.jpg|thumb|right|150px|Thrombosis of cranial mesenteric artery caused by Strongylus vulgaris larvae (Courtesy of Bristol BioMed Image Archive)]]
 
===Horses===
 
 
* E.g. [[Strongylus vulgaris|'''''Strongylus vulgaris''''']] larvae migrating in cranial mesenteric artery in horse
 
** Cause arteritis with thickening of wall
 
*** Due to fibrin and debris deposition and hypersensitivity reaction
 
** Leads to vasoconstriction
 
*** May occlude lumen and encourage thromboemboli.
 
** Can cause ischaemic necrosis of a segment of [[Small Intestine - Anatomy & Physiology|small intestine]]
 
** Is less common now that [[Strongylus vulgaris|'''''Strongylus vulgaris''''']]  infections are declining.
 
* E.g. '''equine''' [[Intestines Fibrinous/Haemorrhagic Enteritis - Pathology#Salmonellosis|'''salmonellosis''']].
 
[[Image:Infaction of the small bowel.jpg|thumb|right|150px|Infarction of the small bowel (Courtesy of Bristol BioMed Image Archive)]]
 
 
===Small Animals===
 
 
* Especially dogs
 
* '''Road traffic accidents''' produce and infact in the gut.
 
* '''Renal disease''' also causes infarction.
 
** Particularly nephrotic syndrome.
 
** Anticoagulant proteins are lost in the urine, leading to a prothrombic state in the ciruclation.
 
 
===Pathology===
 
 
* Similar to that caused by venous congestion.
 
* See sharply delineated dark areas in bowel that are flaccid with loss of tone. 
 
** These become necrotic followed later by peritonitis.
 
 
[[Category:Intestines,_Small_and_Large_-_Pathology]]
 
[[Category:Intestines,_Small_and_Large_-_Pathology]]

Latest revision as of 18:34, 15 February 2011

Intestine - Vascular Disturbances

Vascular disturbances cause obstruction of efferent veins, blockage of afferent arteries or reduced blood flow through unobstructed circulation. All have similar effects on the intestine.

Effects of Intestinal Hypoxia

  • Intestinal hypoxia is induced by vasular distrubances (above).
  • Timescale:
    • 10 – 30 minutes - separation of epithelium from basement membrane.
    • 1 - 2 hours - villus destruction.
    • 2 hours - necrosis of crypt cells.
    • 4 - 5 hours - all mucosa necrotic, sloughed.

Pages in category "Intestine - Vascular Disturbances"

The following 2 pages are in this category, out of 2 total.