Difference between revisions of "Liver Pigmentation"
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==Congenital melanosis== | ==Congenital melanosis== | ||
| − | + | *in calves and lambs | |
| + | *black discoloration of small irregular portions of the [[Liver - Anatomy & Physiology|liver]] | ||
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==Haemosiderin== | ==Haemosiderin== | ||
| − | + | *in chronic passive congestion and surrounding areas where there has been prior necrosis and haemorrhage | |
| − | + | *found within the Kuppfer cells | |
| − | + | *use Perls' stain | |
==Lipofuscin== | ==Lipofuscin== | ||
| − | + | *an insoluble golden brown pigment which occurs within hepatocytes | |
| − | + | *use Schmorl's stain - dark blue | |
| − | + | *increases with age - called the ''''senility' pigment''' | |
| + | *it is commonly seen in hepatocytes near to the centrilobular vein in older cats | ||
| + | *no clinical significance | ||
==Bile== | ==Bile== | ||
| − | + | *especially prominent in obstructive jaundice | |
| − | + | *discolours the tissues green | |
| − | + | *intrahepatic bile canaliculi are distended with a greenish pigment - called '''bile plugs''' | |
| − | + | *larger foci are seen in long standing cases when the hepatocytes rupture: the discharged bile is then surrounded by macrophages and perhaps giant cells - called '''bile lakes''' | |
| − | + | *use Fouchet stain - green | |
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| − | == | + | ==Test yourself with the Liver Pathology Flashcards== |
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| + | [[Liver_Flashcards_-_Pathology|Liver Pathology Flashcards]] | ||
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[[Category:Liver_-_Degenerative Pathology]] | [[Category:Liver_-_Degenerative Pathology]] | ||
| − | [[Category: | + | [[Category:To_Do_-_Clinical]] |
Revision as of 18:39, 15 February 2011
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Congenital melanosis
- in calves and lambs
- black discoloration of small irregular portions of the liver
Haemosiderin
- in chronic passive congestion and surrounding areas where there has been prior necrosis and haemorrhage
- found within the Kuppfer cells
- use Perls' stain
Lipofuscin
- an insoluble golden brown pigment which occurs within hepatocytes
- use Schmorl's stain - dark blue
- increases with age - called the 'senility' pigment
- it is commonly seen in hepatocytes near to the centrilobular vein in older cats
- no clinical significance
Bile
- especially prominent in obstructive jaundice
- discolours the tissues green
- intrahepatic bile canaliculi are distended with a greenish pigment - called bile plugs
- larger foci are seen in long standing cases when the hepatocytes rupture: the discharged bile is then surrounded by macrophages and perhaps giant cells - called bile lakes
- use Fouchet stain - green