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| − | ==Effusions==
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| − | | + | |pagetitle =Effusions |
| − | *Increased amount of fluid in [[Peritoneal cavity - Anatomy & Physiology|peritoneal]], pleural or pericardial cavity
| + | |pagebody =<div style="text-align: left; direction: ltr; margin-left: 1em;"> |
| − | *Not a disease in itself
| + | '''Effusions''' are increased amounts of fluid in the [[Peritoneal Cavity - Anatomy & Physiology|peritoneal]], pleural or pericardial cavities. They are not diseases in themselves but they indicate the presence of a pathological process which has altered the local balance of fluid production and removal. |
| − | *Indicates pathological process affecting fluid production and/or removal
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| − | *Classification
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| − | **Based on cell counts and total protein
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| − | ***Transudate
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| − | ***Modified transudate
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| − | ***Exudate
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| − | **Haemorrhage
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| − | **Chylous effusion
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| − | *Transudate and modified transudate are usually present in the clinical sign '''"ascites"'''
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| − | ===[[Transudate]]===
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| − | ===[[Modified Transudate]]===
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| − | ===[[Exudate]]===
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| − | ===[[Haemorrhagic Effusion]]===
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| − | ===Chylous effusion===
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| − | *Opaque, milky
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| − | *Specific gravity > 1.017
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| − | *Total protein > 30g/L (variable)
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| − | *Nucleated cells 1.5 - 20 x 10e9/L
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| − | *Small [[Lymphocytes - WikiBlood|lymphocytes]], mature [[Neutrophils - WikiBlood|neutrophils]], variable [[Macrophages - WikiBlood|macrophages]])
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| − | *Chyle
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| − | **Triglycerides in fluid > in serum
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| − | **Cholesterol in fluid < in serum
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| − | **Formation of "cream top" (chylomicrons) if refrigerated
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| − | **Does not deparate on centrifugation
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| − | **Sudan III staining lipid droplets
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| − | ==Ectopic sources of fluid==
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| − | *'''Urine'''
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| − | **Uroabdomen
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| − | **Transudate or modified transudate
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| − | *'''Bile'''
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| − | **[[Peritoneal Cavity Inflammatory - Pathology#Causes of peritonitis|Bile peritonitis]]
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| − | **Green in colour
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| − | **Modified transudate or exudate
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| − | *[[Pancreas - Inflammatory Pathology|'''Pancreatitis''']]
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| − | **Modified transudate or exudate
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| | + | The classification of effusions is based on the '''total cell count''' and '''total protein content''' of the fluid: |
| | + | *[[Transudate|'''Transudates''']] and [[Modified Transudate|'''modified transudates''']] have the lowest protein contents and cell counts. They usually result from imbalances in the [[Blood Pressure Physiology#Capillary Fluid Shift Mechanism |Starling forces]]. |
| | + | *[[Exudate|'''Exudates''']] have the highest cell counts and protein contents and usually occur with an inflammatory or neoplastic disease process. |
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| | + | Effusions may also occur when other fluids leak into the abdominal or thoracic cavities. Fluids that may be involved include: |
| | + | *'''Urine''', producing a '''uroabdomen''' (a [[Modified Transudate|modified transudate]] or [[Exudate|exudate]]). |
| | + | *'''Bile''', producing [[Peritonitis#Causes of peritonitis|'''bile peritonitis''']] (a [[Modified Transudate|modified transudate]] or [[Exudate|exudate]])). |
| | + | *'''Pancreatic juices''' leaking in [[Pancreas - Inflammatory Pathology|'''pancreatitis''']] (producing a [[Modified Transudate|modified transudate]] or [[Exudate|exudate]]). |
| | + | *'''Blood''', producing a '''[[Haemoabdomen|haemoabdomen]]''' (a [[Haemorrhagic Effusion|haemorrhagic effusion]]). |
| | + | *'''Chyle''' (or lymph), producing a [[Chylous Effusion|chylous effusion]] in the thorax or abdomen. |
| | + | *'''Pseudochyle''', a mixture of cellular debris and lipid that may resemble a [[Chylous Effusion|chylous effusion]]. |
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| | + | </div> |
| | + | |contenttitle =Content |
| | + | |contentbody =<big><b> |
| | + | <categorytree mode=pages>Effusions</categorytree> |
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| | + | </b></big> |
| | + | | logo =path-logo.png |
| | + | }} |
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| | [[Category:Peritoneal Cavity - Pathology]] | | [[Category:Peritoneal Cavity - Pathology]] |