Difference between revisions of "Muscles Inflammatory - Pathology"

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#redirect[[:Category:Muscles - Inflammatory Pathology]]
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==Myositis==
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[[Bacterial Myositis]]
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===[[Viral Myositis]]===
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===[[Parasitic Myositis]]===
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===[[Immune-Mediated Myositis]]===
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===Idiopathic myositis===
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====Canine polymyositis====
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*DOES NOT include [[Masticatory Muscle Myositis]]
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*Rare
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*Clinical signs:
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**Muscle pain
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**Fever
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**Weakness, particularly in hind limbs
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*Grossly:
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**Inflammation is accompanied by muscle necrosis and regeneration
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*Histologically:
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**Inflammatory foci with lymphocytes, plasma cells and occasionally eosinophils
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*Possibly immunological cause
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*Single biopsy may not be enough to make the diagnosis as it tends to be multifocal and disseminated
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*Lesions similar to some infectious causes (such as ''[[Toxoplasma gondii]]'')
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[[Category:Muscles - Inflammatory Pathology]]
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====Canine bilateral extraocular polymyositis====
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*In Golden retrievers
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*Very rare
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*Clinical signs:
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**Acute bilateral exophthalmos
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*Involves only extraocular muscles except for retractor blbi
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*Grossly:
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**Swollen and pale extraocular muscles
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*Histologically:
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**Sterile myositis
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**Multifocal necrosis of myofibres
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**Lymphocytic, histiocytic and plasmacytic infiltrate with few [[Neutrophils|neutrophils]]
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[[Category:Muscles - Inflammatory Pathology]]
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====Bovine and ovine eosinophilic myositis====
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*Unknown aetiology
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*Major cell involved is eosinphil
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*Usually noticed at slaughter - green muscle discoloration
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*May be caused by degenteration of [[Sarcocystis|''Sarcocystis'' spp.]]
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*Grossly:
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**Green discolored areas, well demarcated
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**Mostly in muscles of back and thighs
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*Histologically:
 +
**Massive eosinophil infiltration
 +
**Muscle fibres may degenerate
 +
**In old lesions - endimysial fibrosis, myofibre atrophy, some regeneration, lymphocytes, plasma cells, macrophages and few eosinophils
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**Capsule may form
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[[Category:Muscles - Inflammatory Pathology]]
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[[Category:Musculoskeletal System - Pathology]]

Revision as of 19:02, 3 March 2011

Myositis

Bacterial Myositis


Viral Myositis

Parasitic Myositis

Immune-Mediated Myositis

Idiopathic myositis

Canine polymyositis

  • DOES NOT include Masticatory Muscle Myositis
  • Rare
  • Clinical signs:
    • Muscle pain
    • Fever
    • Weakness, particularly in hind limbs
  • Grossly:
    • Inflammation is accompanied by muscle necrosis and regeneration
  • Histologically:
    • Inflammatory foci with lymphocytes, plasma cells and occasionally eosinophils
  • Possibly immunological cause
  • Single biopsy may not be enough to make the diagnosis as it tends to be multifocal and disseminated
  • Lesions similar to some infectious causes (such as Toxoplasma gondii)


Canine bilateral extraocular polymyositis

  • In Golden retrievers
  • Very rare
  • Clinical signs:
    • Acute bilateral exophthalmos
  • Involves only extraocular muscles except for retractor blbi
  • Grossly:
    • Swollen and pale extraocular muscles
  • Histologically:
    • Sterile myositis
    • Multifocal necrosis of myofibres
    • Lymphocytic, histiocytic and plasmacytic infiltrate with few neutrophils


Bovine and ovine eosinophilic myositis

  • Unknown aetiology
  • Major cell involved is eosinphil
  • Usually noticed at slaughter - green muscle discoloration
  • May be caused by degenteration of Sarcocystis spp.
  • Grossly:
    • Green discolored areas, well demarcated
    • Mostly in muscles of back and thighs
  • Histologically:
    • Massive eosinophil infiltration
    • Muscle fibres may degenerate
    • In old lesions - endimysial fibrosis, myofibre atrophy, some regeneration, lymphocytes, plasma cells, macrophages and few eosinophils
    • Capsule may form