Difference between revisions of "Sjorgren’s-like syndrome"
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| − | + | == Introduction<br> == | |
| − | == Introduction == | ||
| − | This is a rare syndrome is a complex of | + | This is a rare syndrome is a complex of Xerophthalmia and xerostomia due to lymphocyte-mediated destruction of exocrine glands of [[Salivary Glands - Anatomy & Physiology|salivary glands]]. Both those terms refer to cessation of production of tear or [[Salivary Glands - Anatomy & Physiology#Saliva|saliva]] production respectively. It may be caused by a primary autoimmune defect or part of another autoimmune condition.<br> |
| − | Other causes of xerostomia include dysautonomia, infectious sialadenitis, neoplasia, salivary amyloidosis, head and neck radiation, drugs or autolytic disease. | + | Other causes of xerostomia include dysautonomia, infectious sialadenitis, neoplasia, salivary amyloidosis, head and neck radiation, drugs or autolytic disease. <br> |
| + | <br> | ||
| − | == Clinical Signs == | + | == Clinical Signs<br> == |
| − | Keratoconjunctivitis (dry eye), ulcers of the eye, difficulty swallowing, | + | Keratoconjunctivitis (dry eye), ulcers of the eye, difficulty swallowing, stomatitis, gingivitis and glossitis are all possible clinical signs.<br> |
| + | <br> | ||
| − | == Diagnosis == | + | == Diagnosis<br> == |
| − | Diagnosis by elimination of all other causes of these clinical signs. | + | Diagnosis by elimination of all other causes of these clinical signs.<br> |
| + | <br> | ||
| − | == Treatment == | + | == Treatment<br> == |
| − | None | + | None.<br> |
| − | Supportive treatments to treat clinical signs can be used such as eye lubrication, cleaning and cleansing the mouth and pain relief. | + | Supportive treatments to treat clinical signs can be used such as eye lubrication, cleaning and cleansing the mouth and pain relief.<br> |
| + | <br> | ||
| − | == Prognosis == | + | == Prognosis<br> == |
| − | Guarded to Poor | + | Guarded to Poor<br> |
| + | <br> | ||
| − | + | == References<br> == | |
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| − | + | Merck & Co (2008) The Merck Veterinary Manual (Eighth Edition) Merial<br>Nelson, R.W. and Couto, C.G. (2009) Small Animal Internal Medicine (Fourth Edition) Mosby Elsevier. <br>Tilley, L.P. and Smith, F.W.K.(2004)The 5-minute Veterinary Consult (Third edition) Lippincott, Williams & Wilkins. <br><br> | |
| − | + | '''<br>''' | |
| − | + | [[Category:Salivary_Glands_-_Pathology]] [[Category:To_Do_-_Review]] | |
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| − | [[Category:Salivary_Glands_-_Pathology]] [[Category: | ||
Revision as of 13:08, 11 March 2011
Introduction
This is a rare syndrome is a complex of Xerophthalmia and xerostomia due to lymphocyte-mediated destruction of exocrine glands of salivary glands. Both those terms refer to cessation of production of tear or saliva production respectively. It may be caused by a primary autoimmune defect or part of another autoimmune condition.
Other causes of xerostomia include dysautonomia, infectious sialadenitis, neoplasia, salivary amyloidosis, head and neck radiation, drugs or autolytic disease.
Clinical Signs
Keratoconjunctivitis (dry eye), ulcers of the eye, difficulty swallowing, stomatitis, gingivitis and glossitis are all possible clinical signs.
Diagnosis
Diagnosis by elimination of all other causes of these clinical signs.
Treatment
None.
Supportive treatments to treat clinical signs can be used such as eye lubrication, cleaning and cleansing the mouth and pain relief.
Prognosis
Guarded to Poor
References
Merck & Co (2008) The Merck Veterinary Manual (Eighth Edition) Merial
Nelson, R.W. and Couto, C.G. (2009) Small Animal Internal Medicine (Fourth Edition) Mosby Elsevier.
Tilley, L.P. and Smith, F.W.K.(2004)The 5-minute Veterinary Consult (Third edition) Lippincott, Williams & Wilkins.