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Also known as: '''''Alphaviral encephalitis Alphaviral encephalitides —  Eastern equine encephalitis Eastern equine encephalomyelitis EEE Western equine encephalitis Western equine encephalomyelitis WEE Venezuelan equine encephalitis Venezuelan equine encephalomyelitis VEE
{| cellpadding="10" cellspacing="0" border="1"
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| Also known as:
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|'''Alphaviral encephalitis, Alphaviral encephalitides<br>
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'''Eastern equine encephalitis, Eastern equine encephalomyelitis, EEE<br>
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'''Western equine encephalitis, Western equine encephalomyelitis, WEE<br>
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'''Venezuelan equine encephalitis, Venezuelan equine encephalomyelitis, VEE'''
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==Description==
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==Introduction==
 
'''NOTIFIABLE''' and '''ZOONOTIC''' OIE List B, infectious, mosquito-borne diseases of equidae affecting the central nervous system (CNS).  They include:
 
'''NOTIFIABLE''' and '''ZOONOTIC''' OIE List B, infectious, mosquito-borne diseases of equidae affecting the central nervous system (CNS).  They include:
 
*Eastern Equine Encephalitis (EEE)
 
*Eastern Equine Encephalitis (EEE)
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==Aetiology==
 
==Aetiology==
[[Equine Encephalitis Virus|See this page for details of the causal pathogens]].  Some of the virus strains can infect swine<ref>Karsted, L, Hansen, R.P (1959) Natural and experimental infections in swine with the virus of eastern equine encephalomyelitis, ''J Infect Dis'' 105:293-296.  In: Bertone, J.J (2010) Viral Encephalitis in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), ''Saunders'', Chapter 12</ref>, poultry and other farmed birds including quail and ratites.<ref name="multiple">Bertone, J.J (2010) Viral Encephalitis in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), ''Saunders'', Chapter 12</ref>  Isolated cases have also been noted in cattle<ref>Pursell, A.R, Mitchell, F.E, Seibold, H.R (1976) Naturally occurring and experimentally induced eastern encephalomyelitis in calves, ''J Am Vet Med Assoc'', 169:1101-1103.  In: Bertone, J.J (2010) Viral Encephalitis in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), ''Saunders'', Chapter 12</ref>, sheep and non-domestic ungulates.<ref name="multiple">Bertone, J.J (2010) Viral Encephalitis in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), ''Saunders'', Chapter 12</ref>  Some strains are potential agents of biowarfare or bioterrorism<ref>Steele, K.E, Twenhafel, N.A (2010) Review Paper: Pathology of Animal Models of Alphavirus Encephalitis. ''Vet Pathol.'' Jun 15. [Epub ahead of print].</ref>.
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See this page for details of the [[Equine Encephalitis Virus|equine encephalitis causal pathogens]].  Some of the virus strains can infect swine<ref>Karsted, L, Hansen, R.P (1959) Natural and experimental infections in swine with the virus of eastern equine encephalomyelitis, ''J Infect Dis'' 105:293-296.  In: Bertone, J.J (2010) Viral Encephalitis in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), ''Saunders'', Chapter 12</ref>, poultry and other farmed birds including quail and ratites.<ref name="multiple">Bertone, J.J (2010) Viral Encephalitis in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), ''Saunders'', Chapter 12</ref>  Isolated cases have also been noted in cattle<ref>Pursell, A.R, Mitchell, F.E, Seibold, H.R (1976) Naturally occurring and experimentally induced eastern encephalomyelitis in calves, ''J Am Vet Med Assoc'', 169:1101-1103.  In: Bertone, J.J (2010) Viral Encephalitis in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), ''Saunders'', Chapter 12</ref>, sheep and non-domestic ungulates.<ref name="multiple">Bertone, J.J (2010) Viral Encephalitis in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), ''Saunders'', Chapter 12</ref>  Some strains are potential agents of biowarfare or bioterrorism<ref>Steele, K.E, Twenhafel, N.A (2010) Review Paper: Pathology of Animal Models of Alphavirus Encephalitis. ''Vet Pathol.'' Jun 15. [Epub ahead of print].</ref>.
    
==Epidemiology==
 
==Epidemiology==
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==Signalment==
 
==Signalment==
Unvaccinated adult horses and other equids (for '''VEE in donkeys''' [[Venezuelan Equine Encephalomyelitis (VEE) - Donkey|'''see here''']]) are at risk in areas with suitable vectors.  Vaccinated horses can still develop the disease, particularly if they are young or old.
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Unvaccinated adult horses and other equids ([[Venezuelan Equine Encephalomyelitis (VEE) - Donkey|'''VEE in donkeys''']]) are at risk in areas with suitable vectors.  Vaccinated horses can still develop the disease, particularly if they are young or old.
    
==Clinical Signs==
 
==Clinical Signs==
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===Vector control===
 
===Vector control===
 
Responsible use of insecticides and repellents<ref name="same">Pasquini, C, Pasquini S, Woods, P (2005) '''Guide to Equine Clinics Volume 1: Equine Medicine''', third edition, p266, SUDZ publishing.</ref>, elimination of standing water, and stable screening will all help to reduce viral transmission.  Environmental application of insecticides may be useful in endemic areas or during an outbreak.<ref name="multiple">Bertone, J.J (2010) Viral Encephalitis in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), ''Saunders'', Chapter 12</ref>  Horses infected with Venezuelan EEV should be isolated for 3 weeks after complete recovery.<ref name="same">Pasquini, C, Pasquini S, Woods, P (2005) '''Guide to Equine Clinics Volume 1: Equine Medicine''', third edition, p266, SUDZ publishing.</ref>
 
Responsible use of insecticides and repellents<ref name="same">Pasquini, C, Pasquini S, Woods, P (2005) '''Guide to Equine Clinics Volume 1: Equine Medicine''', third edition, p266, SUDZ publishing.</ref>, elimination of standing water, and stable screening will all help to reduce viral transmission.  Environmental application of insecticides may be useful in endemic areas or during an outbreak.<ref name="multiple">Bertone, J.J (2010) Viral Encephalitis in Reed, S.M, Bayly, W.M. and Sellon, D.C (2010) '''Equine Internal Medicine''' (Third Edition), ''Saunders'', Chapter 12</ref>  Horses infected with Venezuelan EEV should be isolated for 3 weeks after complete recovery.<ref name="same">Pasquini, C, Pasquini S, Woods, P (2005) '''Guide to Equine Clinics Volume 1: Equine Medicine''', third edition, p266, SUDZ publishing.</ref>
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{{Learning
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|literature search = [http://www.cabdirect.org/search.html?q=%28%28title%3A%28%22EEE%22%29%29%29+OR+%28%28title%3A%28%22Eastern+equine+encephalomyelitis%22%29%29%29+OR+%28%28title%3A%28%22Eastern+equine+encephalitis%22%29%29%29 Eastern Equine Encephalomyelitis publications]
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[http://www.cabdirect.org/search.html?q=%28%28title%3A%28%22WEE%22%29%29%29+OR+%28%28title%3A%28%22Western+equine+encephalomyelitis%22%29%29%29+OR+%28%28title%3A%28%22Western+equine+encephalitis%22%29%29%29 Western Equine Encephalomyelitis publications]
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[http://www.cabdirect.org/search.html?q=%28%28title%3A%28%22VEE%22%29%29%29+OR+%28%28title%3A%28%22Venezuelan+equine+encephalomyelitis%22%29%29%29+OR+%28%28title%3A%28%22Venezuelan+equine+encephalitis%22%29%29%29 Venezuelan Equine Encephalomyelitis publications]
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[http://www.cabdirect.org/search.html?q=%28%28title%3A%28treatment%29%29%29+AND+%28%28%28%28%28%28title%3A%28%22EEE%22%29%29%29+OR+%28%28title%3A%28%22Eastern+equine+encephalomyelitis%22%29%29%29+OR+%28%28title%3A%28%22Eastern+equine+encephalitis%22%29%29%29%29%29+OR+%28%28%28%28title%3A%28%22WEE%22%29%29%29+OR+%28%28title%3A%28%22Western+equine+encephalomyelitis%22%29%29%29+OR+%28%28title%3A%28%22Western+equine+encephalitis%22%29%29%29%29%29+OR+%28%28%28%28title%3A%28%22VEE%22%29%29%29+OR+%28%28title%3A%28%22Venezuelan+equine+encephalomyelitis%22%29%29%29+OR+%28%28title%3A%28%22Venezuelan+equine+encephalitis%22%29%29%29%29%29%29%29 Equine Togaviral Encephalomyelitis Treatment publications]
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==References==
 
==References==
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[[Category:Horse]]
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[[Category:Expert_Review]]
 
[[Category:Expert_Review]]
 
[[Category:Zoonoses]]
 
[[Category:Zoonoses]]
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[[Category:Neurological Diseases - Horse]]
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