Difference between revisions of "Carcinoma"
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*Highly invasive and infiltrative | *Highly invasive and infiltrative | ||
*Metastases to the [[Liver - Anatomy & Physiology|liver]], visceral serosa, abdominal [[Lymph Nodes - Anatomy & Physiology|lymph nodes]], [[Spleen - Anatomy & Physiology|spleen]], [[Adrenal Glands - Anatomy & Physiology|adrenals]] etc. | *Metastases to the [[Liver - Anatomy & Physiology|liver]], visceral serosa, abdominal [[Lymph Nodes - Anatomy & Physiology|lymph nodes]], [[Spleen - Anatomy & Physiology|spleen]], [[Adrenal Glands - Anatomy & Physiology|adrenals]] etc. | ||
| − | *Similar to malignant ovarian tumours - implant on the [[Peritoneal | + | *Similar to malignant ovarian tumours - implant on the [[Peritoneal Cavity - Anatomy & Physiology|peritoneum]] |
===Gross appearance=== | ===Gross appearance=== | ||
| Line 67: | Line 67: | ||
**More common than sarcomas | **More common than sarcomas | ||
**Sometimes very scirrhous | **Sometimes very scirrhous | ||
| − | **May resemble chronic [[Peritonitis | + | **May resemble chronic [[Peritonitis|peritonitis]] when present with ascites |
**Absence of adhesions | **Absence of adhesions | ||
| + | |||
| + | {{Learning | ||
| + | |Vetstream = [https://www.vetstream.com/canis/search?s=carcinoma carcinoma] | ||
| + | }} | ||
[[Category:Liver,_Primary_Tumours]] | [[Category:Liver,_Primary_Tumours]] | ||
Latest revision as of 20:25, 25 June 2016
Primary Liver Tumours
Hepatocytic
- more in dogs and cats
Gross
- can be difficult to distinguish grossly from adenomas
- usually one single large mass and additional smaller masses (intrahepatic metastases)
- may have features of malignancy such as internal necrosis and haemorrhage
Microscopically
- can be very variable appearing as sheets or cords of neoplastic cells
- cells generally smaller with a higher nucleus to cytoplasmic ratio
Cholangiocellular - bile duct
- more common than adenoma
- reported in all species (mostly dogs and cats)
Gross
- usually multiple whitish umbilicated nodules that are present diffusely throughout the liver
- actually look as though they were secondary tumours
- firm on cut surface
- due to fibrosis
Microscopically
- distinctly adenocarcinomatous
- ductal and acinar proliferation in abundant fibrous tissue
- sometimes papillary formations
Secondary Liver Tumours
- from a variety of origins
Pancreatic
Image of haemorrhage and pancreatic carcinoma in a cat from Cornell Veterinary Medicine
- In older dogs, more common in Airedale terriers, rare in cats, other species too
- Tend to arise centrally in the gland
- Highly invasive and infiltrative
- Metastases to the liver, visceral serosa, abdominal lymph nodes, spleen, adrenals etc.
- Similar to malignant ovarian tumours - implant on the peritoneum
Gross appearance
- Usually spherical nodules with adhesions to nearby structures
- Single or multiple, variable size
- Greyish or yellow fibrous tissue - firm on cutting
- May show internal necrosis and haemorrhage
- Some tumours may contain cysts wih mucinous content
- Adhesions may occur
Microscopic appearance
- May be well differentiated with normal acini and ducts
- Or diffuse sheet of undifferentiated cells
Endocrine Pancreatic
- Larger than adenomas
- Multilobular
- Invasive into parenchyma and surrounding tissue
- Metastasis into lymph nodes, liver mesentery, omentum
- Few mitotic figures
Peritoneal
- Carcinomas
- Image of carcinoma in a cow's peritoneum from Cornell Veterinary Medicine
- Must be differentiated from mesotheliomas
- More common than sarcomas
- Sometimes very scirrhous
- May resemble chronic peritonitis when present with ascites
- Absence of adhesions
| Carcinoma Learning Resources | |
|---|---|
 To reach the Vetstream content, please select |
Canis, Felis, Lapis or Equis |