Difference between revisions of "Gut Endocrine Function - Anatomy & Physiology"
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+ | |backcolour = FAFAD2 | ||
+ | |linkpage =Endocrine System - Anatomy & Physiology | ||
+ | |linktext =Endocrine System | ||
+ | |maplink = Endocrine System (Content Map) - Anatomy & Physiology | ||
+ | |pagetype =Anatomy | ||
+ | }} | ||
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− | Various regions of the [[Alimentary | + | Various regions of the [[Alimentary - Anatomy & Physiology|Alimentary Tract]] secrete [[Endocrine System - Hormones - Anatomy & Physiology|hormones]] which have various functions within the gastrointestinal tract itself, plus the [[Liver - Anatomy & Physiology|liver]], [[Gall Bladder - Anatomy & Physiology|gall bladder]] and [[Pancreas - Anatomy & Physiology| |
pancreas]]. | pancreas]]. | ||
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|<font color=Purple>Gastrin</font> | |<font color=Purple>Gastrin</font> | ||
− | |G-Cells in [[ | + | |G-Cells in [[Forestomach - Anatomy & Physiology|stomach]] and [[Duodenum - Anatomy & Physiology|duodenum]] |
− | |Stimulates Parietal cells in the [[ | + | |Stimulates Parietal cells in the [[Forestomach - Anatomy & Physiology|stomach]] to secrete HCl and Chief cells to secrete pepsinogen. |
|- | |- | ||
|<font color=Purple>Gastric Inhibitory Peptide</font> | |<font color=Purple>Gastric Inhibitory Peptide</font> | ||
|[[Duodenum - Anatomy & Physiology|Duodenum]]and [[Jejunum - Anatomy & Physiology|Jejunum]] | |[[Duodenum - Anatomy & Physiology|Duodenum]]and [[Jejunum - Anatomy & Physiology|Jejunum]] | ||
− | |Inhibits gastric motility and HCl secretion in the [[ | + | |Inhibits gastric motility and HCl secretion in the [[Forestomach - Anatomy & Physiology|stomach]], induces insulin secretion. |
|- | |- | ||
|<font color=Purple>Ghrelin</font> | |<font color=Purple>Ghrelin</font> | ||
− | |[[ | + | |[[Forestomach - Anatomy & Physiology|Stomach]] and [[Pancreas - Anatomy & Physiology|Pancreas]] |
− | |Increases food intake (by stimulating hunger) at the level of the [[Hypothalamus - Anatomy & Physiology|hypothalamus]]. | + | |Increases food intake (by stimulating hunger) at the level of the [[Endocrine System - Hypothalamus - Anatomy & Physiology|hypothalamus]]. |
|- | |- | ||
|<font color=Purple>Secretin</font> | |<font color=Purple>Secretin</font> | ||
|Crypts of Leiberkuhn in the [[Duodenum - Anatomy & Physiology|Duodenum]] | |Crypts of Leiberkuhn in the [[Duodenum - Anatomy & Physiology|Duodenum]] | ||
− | |Causes secretion of bicarbonate to buffer the pH of the chyme entering the [[Small Intestine | + | |Causes secretion of bicarbonate to buffer the pH of the chyme entering the [[Small Intestine - Anatomy & Physiology|small intestine]]. Also triggers insulin release. |
|- | |- | ||
|<font color=Purple>Somatostatin </font> | |<font color=Purple>Somatostatin </font> | ||
− | |Gastric glands of the [[ | + | |Gastric glands of the [[Forestomach - Anatomy & Physiology|stomach]] |
− | |Inhibits release of gastrin and HCl from the [[ | + | |Inhibits release of gastrin and HCl from the [[Forestomach - Anatomy & Physiology|stomach]], inhibits secretin and cholecystokinin release from the [[Duodenum - Anatomy & Physiology|duodenum]] and inhibits release of glucagon from the [[Pancreas - Anatomy & Physiology|pancreas]]. |
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Revision as of 21:57, 4 August 2008
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Various regions of the Alimentary Tract secrete hormones which have various functions within the gastrointestinal tract itself, plus the liver, gall bladder and pancreas.
Many of the hormones act in a paracrine fashion, exerting their effect on cells close to the secretion site without travelling in the bloodstream.
Hormone | Site of Secretion within GIT | Action |
---|---|---|
Cholecystokinin | Duodenum | Stimulates digestion of fat and protein by causing release of digestive enzymes and bile from the pancreas and gall bladder. |
Gastrin | G-Cells in stomach and duodenum | Stimulates Parietal cells in the stomach to secrete HCl and Chief cells to secrete pepsinogen. |
Gastric Inhibitory Peptide | Duodenumand Jejunum | Inhibits gastric motility and HCl secretion in the stomach, induces insulin secretion. |
Ghrelin | Stomach and Pancreas | Increases food intake (by stimulating hunger) at the level of the hypothalamus. |
Secretin | Crypts of Leiberkuhn in the Duodenum | Causes secretion of bicarbonate to buffer the pH of the chyme entering the small intestine. Also triggers insulin release. |
Somatostatin | Gastric glands of the stomach | Inhibits release of gastrin and HCl from the stomach, inhibits secretin and cholecystokinin release from the duodenum and inhibits release of glucagon from the pancreas. |