Difference between revisions of "Picornaviridae"
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| + | =Introduction= | ||
| + | |||
| + | |||
| + | =Morphology= | ||
| + | *Very small RNA viruses | ||
| + | *Much antigenic variation | ||
| + | *Subtypes evolve and do not cross-protect | ||
| + | *4 capsid proteins (VP1-VP4), with VP1 providing neutralizing target | ||
| + | |||
| + | =Virulence and Pathogenesis= | ||
| + | *Cytopathic effect of all viruses is an overnight '''cell rounding''' and '''pyknosis''' | ||
| + | |||
| + | =Epidemiology= | ||
| + | *Very resistant | ||
| + | *Can survive several months on '''fomites''' | ||
| + | *Infect via upper respiratory tract or buccal cavity and spread to target organs after viremia | ||
| + | |||
| + | =Types and Subtypes= | ||
| + | 3 Main Genera: | ||
| + | ===Enteroviruses=== | ||
| + | *[[Swine Vesicular Disease]] | ||
| + | *[[Porcine Enterovirus]] | ||
| + | ===Apthoviruses=== | ||
| + | *[[Foot and Mouth Disease (FMDV)]] | ||
| + | ===Rhinoviruses=== | ||
| + | *Subclinical cold viruses | ||
*Equine rhinovirus (picornavirus type 1 and 2) in [[Nasal Cavity Inflammatory - Pathology#Infectious causes of rhinitis|rhinitis]], see [[Respiratory Viral Infections - Pathology#Equine rhinovirus|respiratory infections]] | *Equine rhinovirus (picornavirus type 1 and 2) in [[Nasal Cavity Inflammatory - Pathology#Infectious causes of rhinitis|rhinitis]], see [[Respiratory Viral Infections - Pathology#Equine rhinovirus|respiratory infections]] | ||
*Bovine rhinovirus may cause mild [[Respiratory Viral Infections - Pathology#Bovine rhinovirus|respiratory infections]] | *Bovine rhinovirus may cause mild [[Respiratory Viral Infections - Pathology#Bovine rhinovirus|respiratory infections]] | ||
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*[[Cavity & Gingiva - Pathology#Swine Vesicular Disease|Swine Vesicular Disease Virus]] | *[[Cavity & Gingiva - Pathology#Swine Vesicular Disease|Swine Vesicular Disease Virus]] | ||
**May cause [[Viral skin infections - Pathology#Other viruses|skin lesions]] | **May cause [[Viral skin infections - Pathology#Other viruses|skin lesions]] | ||
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Revision as of 17:37, 22 October 2008
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This article is still under construction. |
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Introduction
Morphology
- Very small RNA viruses
- Much antigenic variation
- Subtypes evolve and do not cross-protect
- 4 capsid proteins (VP1-VP4), with VP1 providing neutralizing target
Virulence and Pathogenesis
- Cytopathic effect of all viruses is an overnight cell rounding and pyknosis
Epidemiology
- Very resistant
- Can survive several months on fomites
- Infect via upper respiratory tract or buccal cavity and spread to target organs after viremia
Types and Subtypes
3 Main Genera:
Enteroviruses
Apthoviruses
Rhinoviruses
- Subclinical cold viruses
- Equine rhinovirus (picornavirus type 1 and 2) in rhinitis, see respiratory infections
- Bovine rhinovirus may cause mild respiratory infections
Aphthoviruses
- Foot and Mouth Disease Virus
- May also involve muscles
- May cause skin lesions
Enteroviruses
- Swine Vesicular Disease Virus
- May cause skin lesions