Difference between revisions of "Joint Response to Injury"

Revision as of 20:04, 13 August 2009

Articular cartilage has limited ability to regenerate
- Superficial defects are long standing
  - Chondrocyte hyperplasia is ineffective at filling the defect
  - Non-painful
- Defects reaching subchondral bone
  - Filled with vascular fibroous tissue undergoing metaplasia into cartilage
  - Painful
- Fibrillation - loss of proteoglycans -> condensation of collagen fibres -> fraying of surface
- Eburnation - loss of articular cartilage -> exposure of subchondral bone -> becomes dense and polished
Synovial membranes respond by:
- Villous hypertrophy
  - +/- synovitis
- Hyperplasia

@@ Line 1: / Line 1: @@
+{{review}}
+{{toplink
+|backcolour =CDE472
+|linkpage =Musculoskeletal System - Pathology
+|linktext =Musculoskeletal System
+|maplink = Musculoskeletal System (Content Map) - Pathology
+|pagetype =Pathology
+|sublink1=Joints - Pathology
+|subtext1=JOINTS
+}}
+<br>
 ===Causes of injury ===
@@ Line 14: / Line 26: @@
 ***Non-painful
 **Defects reaching subchondral bone
-***Filled with vascular fibroous tissue undergoing [[Cell Growth Disorders#Metaplasia|metaplasia]] into cartilage
+***Filled with vascular fibroous tissue undergoing [[Disorders of Cell Growth - Pathology#Metaplasia|metaplasia]] into cartilage
 ***Painful
 **Fibrillation - loss of proteoglycans -> condensation of collagen fibres -> fraying of surface
@@ Line 20: / Line 32: @@
 *Synovial membranes respond by:
 **Villous hypertrophy
-***+/- synovitis
+***+/- [[Joints Inflammatory - Pathology|synovitis]]
 **Hyperplasia
-[[Category:Joints - Pathology|A]]