Difference between revisions of "IGF-1 - Anatomy & Physiology"

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==Insulin-like growth factors==
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IGF-1 is one of a number of Insulin-like growth factors.
  
==Overview==
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Insulin-Like Growth Factors are produced by many different tissues and have local (paracrine and autocrine - see [[Hormones - Anatomy & Physiology|hormones]] for further details) effects.
  
[[Image:IGF1.png|250px|thumb|right|Danielle Keller
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They bind to carrier proteins to extend their half life in the blood.
2007 '''Schematic structure of Insulin-like growth factor-1.''']]
 
  
IGF-1 is one of a number of insulin-like growth factors. Insulin-like growth factors are produced by many different tissues and have local paracrine and autocrine effects. (see [[Hormones - Anatomy & Physiology|hormones]] for further details). They bind to carrier proteins to extend their half life in the blood. The [[Liver - Anatomy & Physiology|'''liver''']] is the main source of IGF-1. Hormones that directly stimulate Insulin-like growth factor-I (IGF-I) include growth hormone, insulin and oestradiol.Growth hormone is the main regulator of IGF-I production in the liver and insulin and oestradiol are stimulatory in other tissues.
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The Liver is the main source of IGF-1.
  
 
==Actions of IGF-1==
 
==Actions of IGF-1==
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*Increased protein synthesis
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*Increased chondrogenesis
  
Increased '''protein synthesis''' and increased '''chondrogenesis''', both promoting growth.
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*GROWTH
  
 
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[[Category:Endocrine System]]
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[[Category:Endocrine System - Anatomy & Physiology]]
 
[[Category:A&P Done]]
 

Revision as of 16:20, 29 August 2010

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PITUITARY GLAND



Insulin-like growth factors

IGF-1 is one of a number of Insulin-like growth factors.

Insulin-Like Growth Factors are produced by many different tissues and have local (paracrine and autocrine - see hormones for further details) effects.

They bind to carrier proteins to extend their half life in the blood.

The Liver is the main source of IGF-1.

Actions of IGF-1

  • Increased protein synthesis
  • Increased chondrogenesis
  • GROWTH