Difference between revisions of "Eosinopenia"
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− | Eosinopaenia refers to a reduction in the normal number of circulating blood [[Eosinophil|eosinophils]]. It ocurs most commonly as part of a | + | ==Description== |
+ | Eosinopaenia refers to a reduction in the normal number of circulating blood [[Eosinophil|eosinophils]]. It ocurs most commonly as part of a stress leucocgram and in other situations that result in an increase in the circulating concentration of glucocorticoids: | ||
*'''Stress leucogram''', with which [[Neutrophilia|neutrophilia]], [[Monocytosis|monocytosis]] and [[Lymphopenia|lymphopaenia]] would also be expected. | *'''Stress leucogram''', with which [[Neutrophilia|neutrophilia]], [[Monocytosis|monocytosis]] and [[Lymphopenia|lymphopaenia]] would also be expected. | ||
− | *''' | + | *'''Hyperadrenocorticism''' (Cushing's disease) results in a similar pattern due to an increase in endogenous glucocorticoids. |
*'''Iatrogenic hyperadrenocorticism''' caused by the administration of corticosteroids, even with the use of topical otic or ophthalmic preparations. | *'''Iatrogenic hyperadrenocorticism''' caused by the administration of corticosteroids, even with the use of topical otic or ophthalmic preparations. | ||
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Corticosteroids are thought to exert a depressive effect on lymphocytes which usually stimulate eosinophil production. | Corticosteroids are thought to exert a depressive effect on lymphocytes which usually stimulate eosinophil production. | ||
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Revision as of 22:36, 31 August 2010
This article is still under construction. |
Description
Eosinopaenia refers to a reduction in the normal number of circulating blood eosinophils. It ocurs most commonly as part of a stress leucocgram and in other situations that result in an increase in the circulating concentration of glucocorticoids:
- Stress leucogram, with which neutrophilia, monocytosis and lymphopaenia would also be expected.
- Hyperadrenocorticism (Cushing's disease) results in a similar pattern due to an increase in endogenous glucocorticoids.
- Iatrogenic hyperadrenocorticism caused by the administration of corticosteroids, even with the use of topical otic or ophthalmic preparations.
Corticosteroids are thought to exert a depressive effect on lymphocytes which usually stimulate eosinophil production.