Difference between revisions of "Feline Herpesvirus 1"
BaraStudent (talk | contribs) |
|||
| (4 intermediate revisions by 2 users not shown) | |||
| Line 1: | Line 1: | ||
| + | {{OpenPagesTop}} | ||
== Introduction == | == Introduction == | ||
| Line 13: | Line 14: | ||
== Clinical Signs == | == Clinical Signs == | ||
| − | Upper respiratory tract signs such as [[rhinitis]], [[tracheitis]] and [[sinusitis]] as well as keratitis and corneal ulcers. In combination with other agents, will cause 'cat flu' which will include sneezing, coughing, gummy eyes, nasal discharge, dyspnoea and conjunctivitis. | + | Upper respiratory tract signs such as [[rhinitis]], [[tracheitis]] and [[sinusitis]] as well as keratitis and [[Corneal Ulceration - Dogs and Cats|corneal ulcers]]. The corneal ulcers intially have a '''dendritic''' appearence, which is considered pathognomic. In combination with other agents, will cause 'cat flu' which will include sneezing, coughing, gummy eyes, nasal discharge, dyspnoea and conjunctivitis. |
== Diagnosis == | == Diagnosis == | ||
| Line 39: | Line 40: | ||
Merck & Co (2008) The Merck Veterinary Manual (Eighth Edition), Merial | Merck & Co (2008) The Merck Veterinary Manual (Eighth Edition), Merial | ||
| − | == | + | {{Learning |
| + | |powerpoints = [[E-Lecture:Feline Herpesvirus-1]] | ||
| + | |Vetstream = [https://www.vetstream.com/felis/Content/Disease/dis60212 Feline herpesvirus disease] | ||
| + | }} | ||
| − | |||
| + | {{review}} | ||
| + | {{OpenPages}} | ||
[[Category:Herpesviridae]] [[Category:Expert_Review - Small Animal]] [[Category:Cat_Viruses]] [[Category:Respiratory_Diseases_-_Cat]] [[Category:Respiratory_Viral_Infections]] | [[Category:Herpesviridae]] [[Category:Expert_Review - Small Animal]] [[Category:Cat_Viruses]] [[Category:Respiratory_Diseases_-_Cat]] [[Category:Respiratory_Viral_Infections]] | ||
[[Category:Hepatitis, Viral]] | [[Category:Hepatitis, Viral]] | ||
Latest revision as of 09:42, 19 January 2016
Introduction
Feline Herpes virus (FHV-1) causes an upper respiratory tract infection: Feline Viral Rhinotracheitis.
Viruses and bacteria are involved in the complex, with the most frequent aetiologic agent being FHV-1, and less frequently feline calicivirus and/or Chlamydophila psittaci. All three agents infect URT respiratory epithelium, although FHV-1 has the highest affinity for this epithelium. Feline calicivirus more frequently infects the oral mucosa -> ulcerative stomatitis and C. felis more frequently infects the conjunctival epithelium -> chronic conjunctivitis. All three together will result in the disease complex 'cat flu'.
Infection of the respiratory epithelium by FHV-1 results in a typical neutrophilic rhinitis with intraepithelial intranuclear eosinophilic inclusion bodies, with expected clinical signs. Resolution of these clinical signs usually occurs by 7-14 days, however, FHV-1 remains latent in the trigeminal ganglion, and can reactivate at times of stress. It can infect the cornea - ulcerative keratitis. FHV- 1 is the most common cause of keratitis and corneal ulcers in cats and gummy eyes in kittens.
Occasional mortality can occur in the kitten or immunocompromised animals usually associated with secondary bacterial infections.
The virus is widespread and common. It can cause serious infections as well as latent infections which can be reactivated on boarding or at other periods of stress.
Clinical Signs
Upper respiratory tract signs such as rhinitis, tracheitis and sinusitis as well as keratitis and corneal ulcers. The corneal ulcers intially have a dendritic appearence, which is considered pathognomic. In combination with other agents, will cause 'cat flu' which will include sneezing, coughing, gummy eyes, nasal discharge, dyspnoea and conjunctivitis.
Diagnosis
Clinical signs and history are usually used as a presumptive diagnosis prior to definitive diagnosis via laboratory tests.
Nasal swabs on first week of infection can be cultured for virus isolation, plus a swab of the eye.
Treatment
For keratitis with corneal ulcers treat with subcutaneous omega interferon and give topical trifluorothymidine (thymidine analogue) on eyes.
Control
Killed and live vaccines are available. Live vaccines have provoked symptoms in immunosuppressed kittens and are no longer used in the UK.
References
Bridger, J and Ruseel, P, (2007) Virology Study Guide, Royal Veterinary College
Ettinger, S.J. and Feldman, E. C. (2000) Textbook of Veterinary Internal Medicine Diseases of the Dog and Cat Volume 2 (Fifth Edition), W.B. Saunders Company
Ettinger, S.J, Feldman, E.C. (2005) Textbook of Veterinary Internal Medicine (6th edition, volume 2), W.B. Saunders Company
Merck & Co (2008) The Merck Veterinary Manual (Eighth Edition), Merial
| Feline Herpesvirus 1 Learning Resources | |
|---|---|
 To reach the Vetstream content, please select |
Canis, Felis, Lapis or Equis |
 Selection of relevant PowerPoint tutorials |
E-Lecture:Feline Herpesvirus-1 |
 |
This article has been peer reviewed but is awaiting expert review. If you would like to help with this, please see more information about expert reviewing. |
Error in widget FBRecommend: unable to write file /var/www/wikivet.net/extensions/Widgets/compiled_templates/wrt67438837a8b333_30348283 Error in widget google+: unable to write file /var/www/wikivet.net/extensions/Widgets/compiled_templates/wrt67438837adfc76_25074000 Error in widget TwitterTweet: unable to write file /var/www/wikivet.net/extensions/Widgets/compiled_templates/wrt67438837b2d012_81140917
|
| WikiVet® Introduction - Help WikiVet - Report a Problem |