Difference between revisions of "Duck Hepatitis Virus"
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| + | {{OpenPagesTop}} | ||
| + | {{Podcasts | ||
| + | |link = https://bloomsbury.mediacore.tv/podcasts/wikivet-english/duck-hepatitis-virus}} | ||
{{Taxobox | {{Taxobox | ||
|name = DHV-II | |name = DHV-II | ||
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|sub-order = | |sub-order = | ||
|super-family = | |super-family = | ||
| − | |family = Astroviridae | + | |family = [[:Category:Astroviridae|Astroviridae]] |
|sub-family = | |sub-family = | ||
|genus = Astrovirus | |genus = Astrovirus | ||
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Also Known As: '''''Duck Viral Hepatitis''''' — '''''DVH''''' — '''''DH''''' | Also Known As: '''''Duck Viral Hepatitis''''' — '''''DVH''''' — '''''DH''''' | ||
| − | Caused By: '''''Duck Hepatitis Virus 1 and 3'' — ''DHV- | + | Caused By: '''''Duck Hepatitis Virus 1 and 3'' — ''DHV-1'' — ''DHV-3'' |
==Introduction== | ==Introduction== | ||
| − | Duck hepatitis is caused by the [[:Category:Enteroviruses|'''enteroviruses''']] DHV- | + | Duck hepatitis is caused by the [[:Category:Enteroviruses|'''enteroviruses''']] DHV-1 and DHV-3. |
It is a '''highly fatal''' disease of ducklings causing very high '''mortality''', '''opisthotonus''' and '''hepatitis'''. | It is a '''highly fatal''' disease of ducklings causing very high '''mortality''', '''opisthotonus''' and '''hepatitis'''. | ||
| − | |||
| − | |||
==Signalment== | ==Signalment== | ||
Ducks are the only species naturally affected. | Ducks are the only species naturally affected. | ||
| − | DHV- | + | DHV-1 occurs only in '''young ducklings''', usually '''<6 weeks''' of age and spreads rapidly within a flock. It is the '''most virulent''' of the three. |
| − | DHV- | + | DHV-2, an astrovirus (duck astrovirus 1), not an enterovirus, has only been reported in outdoor ducks on open fields. |
Duck Hepatitis is not considered zoonotic. | Duck Hepatitis is not considered zoonotic. | ||
==Distribution== | ==Distribution== | ||
| − | DHV- | + | DHV-1 is present worldwide. |
| − | |||
| − | |||
| − | DHV- | + | DHV-2 has only been reported in Norfolk, England and no outbreaks have been recorded since the 1980’s. |
| − | + | DHV-3 has only been reported in the USA. | |
==Clinical Signs== | ==Clinical Signs== | ||
'''Sudden deaths, Opisthotonus, Paresis''', Paralysis, Enopthalmos. | '''Sudden deaths, Opisthotonus, Paresis''', Paralysis, Enopthalmos. | ||
| − | DHV- | + | DHV-1 infection is most virulent. Morbidity is 100%, with mortality <95% up to one week of age, <50% for 1-3 weeks of age and negligible thereafter. Death usually occurs within 1-2 hours of clinical signs. |
| − | Mortality rates are lower in DHV- | + | Mortality rates are lower in DHV-2 infections, reaching only 20%. |
==Diagnosis== | ==Diagnosis== | ||
On post-mortem examination, the '''[[Avian Liver - Anatomy & Physiology|liver]]''' is '''enlarged''', appears '''greenish''' and displays distinct '''ecchymotic haemorrhages'''. | On post-mortem examination, the '''[[Avian Liver - Anatomy & Physiology|liver]]''' is '''enlarged''', appears '''greenish''' and displays distinct '''ecchymotic haemorrhages'''. | ||
| − | Splenic and [[Exotic Urinary System - Anatomy & Physiology#Avian | + | Splenic and [[Exotic Urinary System - Anatomy & Physiology#Avian|kidney]] swelling may also be evident. Cutaneous haemorrhage is often noted. |
On histopathology, '''necrosis''' and inflammatory infiltrate are visible within hepatic cells. | On histopathology, '''necrosis''' and inflammatory infiltrate are visible within hepatic cells. | ||
| − | '''Innoculation''' from liver suspensions can be used for confirmation of all DHVs. | + | '''Innoculation''' from liver suspensions can be used for confirmation of all DHVs using embryonated duck eggs, chicken eggs and tissue culture. |
| − | '''Direct [[immunofluorescence]]''' can also confirm presence of DHV- | + | '''Direct [[immunofluorescence]]''' can also confirm presence of DHV-1. |
'''Virus Neutralisation (VN)''' serological tests can be used to monitor vaccination response and epidemiology. | '''Virus Neutralisation (VN)''' serological tests can be used to monitor vaccination response and epidemiology. | ||
| Line 87: | Line 86: | ||
==Control== | ==Control== | ||
| − | '''Vaccination''' is only commercially available against '''DHV- | + | '''Vaccination''' is only commercially available against '''DHV-1'''. Immunisation involves two or three innoculations. Live, attenuated and inactivated forms are available. |
| − | DHV- | + | DHV-1 can be prevented by '''strict isolation''' in the first 4-5 weeks of life. |
The viruses are resistant to inactivation by heat, acid and some disinfectants. Only 5% phenol and formaldehyde are successful in inactivating the viruses. | The viruses are resistant to inactivation by heat, acid and some disinfectants. Only 5% phenol and formaldehyde are successful in inactivating the viruses. | ||
| Line 103: | Line 102: | ||
==References== | ==References== | ||
| − | + | Gough R.E. and McNulty, M.S. (2007) '''Picornaviridae'''. In: '''Poultry Diseases, 6th Edition''' (eds. Pattison, M., McMullin, P., Bradbury, J., Alexander, D.) ''Saunders, Elsevier'', pp 350-359 | |
| − | + | ||
| + | Woolcock, P.R. (2008) '''Duck Hepatitis'''. In: '''Diseases of Poultry, 12th Edition''' (eds. Saif, Y.M., Fadly A.M., Glissen J.R., McDougald L.R., Nolan L.K., Swayne D.E.) ''Wiley-Blackwell'', pp 373-384 | ||
| + | |||
| + | {{CABI source | ||
| + | |datasheet = [http://www.cabi.org/ahpc/?compid=3&dsid=84184&loadmodule=datasheet&page=2144&site=160 duck hepatitis], [http://www.cabi.org/ahpc/Default.aspx?site=160&page=2144&LoadModule=datasheet&CompID=3&dsID=84185 duck hepatitis virus] and [http://www.cabi.org/ahpc/Default.aspx?site=160&page=2144&LoadModule=datasheet&CompID=3&dsID=84186 duck hepatitis virus type II] | ||
| + | |date =5 June 2011 | ||
| + | }} | ||
| + | <br><br> | ||
| + | |||
| + | {{Dave Cavanagh | ||
| + | |date = 23 August 2011 | ||
| + | }} | ||
| + | {{OpenPages}} | ||
| − | + | [[Category:CABI Expert Review Completed]][[Category:CABI AHPC Pages]] | |
| − | [[Category:CABI Expert Review]] | ||
[[Category:Enteroviruses]] | [[Category:Enteroviruses]] | ||
| + | [[Category:Astroviridae]] | ||
[[Category:Avian Viruses]] | [[Category:Avian Viruses]] | ||
[[Category:Alimentary Diseases - Birds]] | [[Category:Alimentary Diseases - Birds]] | ||
[[Category:Neurological Diseases - Birds]] | [[Category:Neurological Diseases - Birds]] | ||
Latest revision as of 13:31, 17 August 2012
|
| DHV-II | |
|---|---|
| Order | RNA viruses |
| Family | Astroviridae |
| Genus | Astrovirus |
| Species | DHV-II |
| DHV-1 and DHV-III | |
|---|---|
| Order | RNA Viruses |
| Family | Picornaviridae |
| Genus | Enterovirus |
| Species | Duck Hepatitis Virus I and III |
Also Known As: Duck Viral Hepatitis — DVH — DH
Caused By: Duck Hepatitis Virus 1 and 3 — DHV-1 — DHV-3
Introduction
Duck hepatitis is caused by the enteroviruses DHV-1 and DHV-3.
It is a highly fatal disease of ducklings causing very high mortality, opisthotonus and hepatitis.
Signalment
Ducks are the only species naturally affected.
DHV-1 occurs only in young ducklings, usually <6 weeks of age and spreads rapidly within a flock. It is the most virulent of the three.
DHV-2, an astrovirus (duck astrovirus 1), not an enterovirus, has only been reported in outdoor ducks on open fields.
Duck Hepatitis is not considered zoonotic.
Distribution
DHV-1 is present worldwide.
DHV-2 has only been reported in Norfolk, England and no outbreaks have been recorded since the 1980’s.
DHV-3 has only been reported in the USA.
Clinical Signs
Sudden deaths, Opisthotonus, Paresis, Paralysis, Enopthalmos.
DHV-1 infection is most virulent. Morbidity is 100%, with mortality <95% up to one week of age, <50% for 1-3 weeks of age and negligible thereafter. Death usually occurs within 1-2 hours of clinical signs.
Mortality rates are lower in DHV-2 infections, reaching only 20%.
Diagnosis
On post-mortem examination, the liver is enlarged, appears greenish and displays distinct ecchymotic haemorrhages.
Splenic and kidney swelling may also be evident. Cutaneous haemorrhage is often noted.
On histopathology, necrosis and inflammatory infiltrate are visible within hepatic cells.
Innoculation from liver suspensions can be used for confirmation of all DHVs using embryonated duck eggs, chicken eggs and tissue culture.
Direct immunofluorescence can also confirm presence of DHV-1.
Virus Neutralisation (VN) serological tests can be used to monitor vaccination response and epidemiology.
Treatment
No treatment is effective once infected.
Control
Vaccination is only commercially available against DHV-1. Immunisation involves two or three innoculations. Live, attenuated and inactivated forms are available.
DHV-1 can be prevented by strict isolation in the first 4-5 weeks of life.
The viruses are resistant to inactivation by heat, acid and some disinfectants. Only 5% phenol and formaldehyde are successful in inactivating the viruses.
Duck Hepatitis is a Class B disease listed by the Office des International Epizooties and thus any ducks exported require an international veterinary certificate that they are from a DVH free establishment and are not exhibiting clinical signs of DH. Vaccination status must also be disclosed.
| Duck Hepatitis Virus Learning Resources | |
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Duck Hepatitis Virus Flashcards |
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DHV Publications |
References
Gough R.E. and McNulty, M.S. (2007) Picornaviridae. In: Poultry Diseases, 6th Edition (eds. Pattison, M., McMullin, P., Bradbury, J., Alexander, D.) Saunders, Elsevier, pp 350-359
Woolcock, P.R. (2008) Duck Hepatitis. In: Diseases of Poultry, 12th Edition (eds. Saif, Y.M., Fadly A.M., Glissen J.R., McDougald L.R., Nolan L.K., Swayne D.E.) Wiley-Blackwell, pp 373-384
|
This article was originally sourced from The Animal Health & Production Compendium (AHPC) published online by CABI during the OVAL Project. The datasheet was accessed on 5 June 2011. |
 |
This article has been expert reviewed by Prof Dave Cavanagh BSc, PhD, DSc Date reviewed: 23 August 2011 |
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