Difference between revisions of "Porcine Intestinal Spirochaetosis"
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| − | Also Known As | + | {{OpenPagesTop}} |
| + | Also Known As: '''''PIS — Porcine Colonic Spirochaetosis — Spirochaetal Diarrhoea''''' | ||
| − | Caused By | + | Caused By: '''''[[Brachyspira pilosicoli]]'' |
==Introduction== | ==Introduction== | ||
| − | + | [[File:Intestinal spirochetosis - cropped - very high mag.jpg|thumb|200px|right|Intestinal spirochetosis - note the hyperchromatic fuzzy appearance of the brush border adjacent to the lumen. This is the attached spirochaetes. Wikimedia Commons.]] | |
| − | Porcine spirochaetosis is a ''' | + | Porcine spirochaetosis is a '''gastrointestinal disease of pigs''' caused by the '''gram negative anaerobic''' bacterium, '''''[[Brachyspira pilosicoli]]'''''. |
The pathogen colonises the '''lumen and crypts of the large intestine''', attaching firmly at one end of the cell to the epithelium. | The pathogen colonises the '''lumen and crypts of the large intestine''', attaching firmly at one end of the cell to the epithelium. | ||
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Porcine spirochaetosis is present in many significant pig rearing countries, including the '''UK, Europe, Scandinavia, USA, Canada, Brazil and Australasia.''' | Porcine spirochaetosis is present in many significant pig rearing countries, including the '''UK, Europe, Scandinavia, USA, Canada, Brazil and Australasia.''' | ||
| − | Transmission is mainly '''faecal: oral.''' | + | Transmission is mainly '''faecal: oral.''' The bacterium can remain viable in lake water for up to 2 months, providing another route of transmission. Birds and rodents may act as vectors for disease. |
| − | The bacterium can remain viable in lake water for up to 2 months, providing another route of transmission. | ||
| − | Birds and rodents may act as vectors for disease. | ||
==Signalment== | ==Signalment== | ||
| − | ''B. pilosicoli'' has also been isolated from '''people, | + | ''B. pilosicoli'' has also been isolated from '''people, dogs, waterfowl, chickens and guinea pigs.''' Clinical disease is most common in pigs followed by birds. |
| − | Clinical disease is most common in pigs followed by birds. | ||
'''Overcrowding and movement''' of pigs between sites predisposes them to infection and clinical disease. | '''Overcrowding and movement''' of pigs between sites predisposes them to infection and clinical disease. | ||
| + | |||
Infection is most common in 8-14 week old piglets, particularly within 1-2 weeks of moving and mixing batches. | Infection is most common in 8-14 week old piglets, particularly within 1-2 weeks of moving and mixing batches. | ||
==Clinical Signs== | ==Clinical Signs== | ||
| − | Clinical disease is generally '''mild.''' | + | Clinical disease is generally '''mild.''' The signs include '''grey or grey-green [[Diarrhoea|diarrhoea]]''' which may contain blood or mucus, colitis, '''sub-optimal growth rates and feed efficiency.''' Pigs may require up to 28 additional days to reach slaughter weight. |
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| − | ''' | ||
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| − | ''' | ||
Occasionally, pigs may become depressed and lethargic. | Occasionally, pigs may become depressed and lethargic. | ||
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==References== | ==References== | ||
<references/> | <references/> | ||
| − | + | {{CABI source | |
| + | |datasheet = [http://www.cabi.org/ahpc/?compid=3&dsid=68593&loadmodule=datasheet&page=2144&site=160 porcine intestinal spirochaetosis] | ||
| + | |date =11 June 2011 | ||
| + | }} | ||
| + | <br><br><br> | ||
| + | |||
| + | {{review}} | ||
| − | + | {{OpenPages}} | |
| − | [[Category: | + | [[Category:Zoonoses]] |
| + | [[Category:Intestinal Diseases - Pig]] | ||
| + | [[Category:Alimentary Diseases - Birds]] | ||
| + | [[Category:CABI Expert Review]][[Category:CABI AHPC Pages]] | ||
Latest revision as of 14:45, 17 August 2012
Also Known As: PIS — Porcine Colonic Spirochaetosis — Spirochaetal Diarrhoea
Caused By: Brachyspira pilosicoli
Introduction
Porcine spirochaetosis is a gastrointestinal disease of pigs caused by the gram negative anaerobic bacterium, Brachyspira pilosicoli.
The pathogen colonises the lumen and crypts of the large intestine, attaching firmly at one end of the cell to the epithelium.
PIS is also zoonotic and is associated with chronic diarrhoea and rectal bleeding in humans.
This disease is notifiable to the World Organisation for Animal Health (OIE)
Distribution
Porcine spirochaetosis is present in many significant pig rearing countries, including the UK, Europe, Scandinavia, USA, Canada, Brazil and Australasia.
Transmission is mainly faecal: oral. The bacterium can remain viable in lake water for up to 2 months, providing another route of transmission. Birds and rodents may act as vectors for disease.
Signalment
B. pilosicoli has also been isolated from people, dogs, waterfowl, chickens and guinea pigs. Clinical disease is most common in pigs followed by birds.
Overcrowding and movement of pigs between sites predisposes them to infection and clinical disease.
Infection is most common in 8-14 week old piglets, particularly within 1-2 weeks of moving and mixing batches.
Clinical Signs
Clinical disease is generally mild. The signs include grey or grey-green diarrhoea which may contain blood or mucus, colitis, sub-optimal growth rates and feed efficiency. Pigs may require up to 28 additional days to reach slaughter weight.
Occasionally, pigs may become depressed and lethargic.
Diagnosis
B. pilosicoli can be cultured from faeces or intestinal samples and isolated on blood agar with selective antibiotics in anaerobic conditions. Colonies are weakly haemolytic and can be definitively identified as spirochaetes under phase contract or dark field microscopy.
PCR can then confirm species identification.
On post-mortem, animals are in poor body condition and oedema is common between the coils of the large intestine. When the colon is opened, the mucosa is erythematous in patches.
Histologically, a fake brush border of attached spirochaetes is pathognomic.
Treatment
Lincomycin and Tiamulin are the most common antibiotics used against PIS, given in water or by injection.
Control
At risk pigs are sometimes given prophylactic antibiotics although this use is controversial.
Mixing and moving pigs should be avoided where possible.
Feeding meal or mash may reduce the occurrence of diarrhoea.
| Porcine Intestinal Spirochaetosis Learning Resources | |
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References
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This article was originally sourced from The Animal Health & Production Compendium (AHPC) published online by CABI during the OVAL Project. The datasheet was accessed on 11 June 2011. |
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This article has been peer reviewed but is awaiting expert review. If you would like to help with this, please see more information about expert reviewing. |
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