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| |pagetitle =Stomach and Abomasum - Inflammatory Pathology | | |pagetitle =Stomach and Abomasum - Inflammatory Pathology |
− | |pagebody = '''Gastritis''' refers to inflammation of the [[Forestomach - Anatomy & Physiology|stomach]]. | + | |pagebody = '''Gastritis''' refers to inflammation of the [[Monogastric Stomach - Anatomy & Physiology|stomach]]. |
| + | Vesicular gastritis is not seen, as the [[Monogastric Stomach - Anatomy & Physiology|stomach]] has no stratum spinosum. |
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− | |logo = | + | |logo =path-logo.png |
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− | ==[[Gastritis, Fibrinous/ Diptheric]] Gastritis==
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− | ==Haemorrhagic Gastritis==
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− | ===Clinical===
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− |
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− | * Usually only seen post mortem.
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− | * [[Forestomach - Anatomy & Physiology|Stomach]] full of thick tarry clots.
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− | * Occasionally will vomit blood in life.
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− | ===Pathology===
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− | [[Image:haemorrhagic gastritis.jpg|thumb|200px|right|Haemorrhagic gastritis (Courtesy of BioMed Image Archive)]]
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− | ====Gross====
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− | * Wall of [[Forestomach - Anatomy & Physiology|stomach]] is blacked and ulcerated.
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− | ** Red, thickened, necrotic, haemorrhagic mucosa.
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− |
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− | ====Histologically====
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− | * Coagulative necrosis with fibrin, oedema, haemorrhage, and sometimes emphysema.
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− | * May extend deep into submucosa/muscle.
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− | ===Pathogenesis===
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− | * There are several causes of haemorrhagic gastritis
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− | *# Aspirin and non-steroidal anti inflammatory drug toxicity.
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− | *# Peracute / acute infections, e.g.
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− | *#* Swine Fever
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− | *#* Anthrax
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− | *#* Leptospirosis in dogs (''Leptospira icterohaemorrhagiae'').
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− | *#Clostridial disease
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− | *#* e.g. '''Braxy''' (''Clostridium septicum'')
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− | *#** Affects older lambs or yearlings producing sudden death.
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− | *#** Usually seen on sheep grazing on frosted grass so more common in colder areas.
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− | *#** Bacterial exotoxin causes acute abomasitis.
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− | *#** '''Pathology'''- At post mortem the [[Forestomach - Anatomy & Physiology|stomach]] is grossly distended with partially clotted blood. The wall of the [[Forestomach - Anatomy & Physiology|stomach]] is thickened,reddened and oedematous.
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− | *#** Diagnosed by isolation of organism from the [[Forestomach - Anatomy & Physiology|stomach]] wall.
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− | *#** Is now usually vaccinated against (Heptovac 7 in 1 clostridial vaccine).
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− | *# [[Stomach and Abomasum Toxicology - Pathology#Warfarin Poisoning| Warfarin poisoning]].
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− | == Vesicular Gastritis==
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− | * Is not seen, as the [[Forestomach - Anatomy & Physiology|stomach]] has no stratum spinosum.
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− | ==Chronic gastritis==
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− | * Chronic gastritis is usually proliferative rather any other type of gastric inflammation.
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− | * Usually a parasitic cause.
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− | * Occurs mostly in the pig and in cattle.
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− | * '''Pig'''
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− | ** Redworms (''Hyostrongylus'')
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− | ** Seen mostly in sows, and are present in up to 30% of pig herds.
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− | ** Small numbers produce little pathology, but large numbers cause thin sow syndrome.
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− | *** Animals eat well but slowly lose condition.
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− | * '''Cattle'''
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− | ** [[Stomach and Abomasum Parasites - Pathology#Ostertagiasis|Ostertagiasis]] produces a condition similar to thin sow syndrome.
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− | ===Chronic Hypertrophic Gastritis In The Dog===
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− | * Clinically see anorexia, weight loss, anaemia and associated hepatic disease.
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− | * Associated with protein loss into gut.
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− | ====Pathology====
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− | * Hyperplasia of mucosa.
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− | ** Mucosa thrown up into folds.
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− | ** Reduced numbers of parietal cells and increased numbers of goblet cells.
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− | === Chronic Atrophic Gastritis In The Dog===
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− | * Aetiology uncertain.
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− | * '''Grossly:''' (may be difficult to appreciate)
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− | ** Reduced mucosal thickness.
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− | ** Loss of rugae.
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− | * '''Histologically'''
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− | ** Mucosal thinning.
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− | ** Loss of gastric glands.
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− | ** Diffuse inflammatory infiltrate of lymphocytes and plasma cells.
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− | ** Fewer eosinophils in lamina propria.
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| [[Category:Stomach and Abomasum - Pathology]] | | [[Category:Stomach and Abomasum - Pathology]] |