Difference between revisions of "Zygomycosis"
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*Infection is by inhalation and ingestion | *Infection is by inhalation and ingestion | ||
| − | *Infects [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] of the [[Cardiorespiratory System - Anatomy & Physiology|respiratory]] and [[Alimentary - Anatomy & Physiology|alimentary tract]] | + | *Infects [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] of the [[Cardiorespiratory System Overview - Anatomy & Physiology|respiratory]] and [[Alimentary System Overview - Anatomy & Physiology|alimentary tract]] |
**[[Lymph Nodes - Anatomy & Physiology|Lymph nodes]] enlarge and become caseous | **[[Lymph Nodes - Anatomy & Physiology|Lymph nodes]] enlarge and become caseous | ||
| − | **Can cause [[Alimentary - Anatomy & Physiology#Stomach|stomach]] and [[Small Intestine - Anatomy & Physiology|intestinal]] ulcers | + | **Can cause [[Alimentary System Overview - Anatomy & Physiology#Stomach|stomach]] and [[Small Intestine Overview - Anatomy & Physiology|intestinal]] ulcers |
| Line 32: | Line 32: | ||
*Cattle | *Cattle | ||
**Bronchial, mesenteric and mediastinal [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] lesions | **Bronchial, mesenteric and mediastinal [[Lymph Nodes - Anatomy & Physiology|lymph nodes]] lesions | ||
| − | **Ulcers of the [[Nasal | + | **Ulcers of the [[Nasal Cavity - Anatomy & Physiology|nasal cavity]] and [[Abomasum - Anatomy & Physiology|abomasum]] also occur |
| − | **Often contaminate the [[ | + | **Often contaminate the [[Placenta - Anatomy & Physiology|placenta]] |
*Horses, dogs, cats, sheep, mink, guinea-pigs and mice can also be infected | *Horses, dogs, cats, sheep, mink, guinea-pigs and mice can also be infected | ||
| Line 67: | Line 67: | ||
**Many eosinophils | **Many eosinophils | ||
| + | ==Test yourself with the Systemic Mycoses Flashcards== | ||
| + | [[Systemic_Mycoses_-_Flashcards#Zygomycosis|Zygomycosis Flashcards]] | ||
[[Category:Systemic_Mycoses]] | [[Category:Systemic_Mycoses]] | ||
[[Category:To_Do_-_Fungi]] | [[Category:To_Do_-_Fungi]] | ||
| + | [[Category:Subcutaneous Mycoses]] | ||
Latest revision as of 14:20, 22 February 2011
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- Also known as mucormycosis, hyphomycosis and phycomycosis
- Caused by strains of Mucor, Absidia, Rhizopus and Mortierella
- Mucor circinelloides(rare), Rhizomucor pusillus and R. meihi
- Absidia corymbifera often causes zygomycosis in cattle and pigs
- Rhizopus arrhizus, R. microsporus and R. rhizopodormis
- Mortierella wolfi implicated in bovine abortion (mycotic placentitis), M. hygrophila in fowl and M.polycephala in cattle
- Occurs widely in nature
- Infection is by inhalation and ingestion
- Infects lymph nodes of the respiratory and alimentary tract
- Lymph nodes enlarge and become caseous
- Can cause stomach and intestinal ulcers
- Granulomatous lesions which can ulcerate
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- Mostly localised lesions but can be generalised
- Pigs
- Mediastinal and submandibular lymph nodes lesions
- Embolic tumours in the liver and lungs
- Can also be present in gastric ulcers
- Cattle
- Bronchial, mesenteric and mediastinal lymph nodes lesions
- Ulcers of the nasal cavity and abomasum also occur
- Often contaminate the placenta
- Horses, dogs, cats, sheep, mink, guinea-pigs and mice can also be infected
- Microscopically:
- Fragments of non-septate hyphae which are branched and coarse
- Rhizomucor produce a thick, grey mycelium and have short, black, spherical sporangia
- Mucor produce thick, colourless mycelium with no rhizoids. Globose spoangia with small spores are present and sporagiospores are simple or branched.
- Absidia resemble Rhizopus grossly
- Mortierella produce white, velvet colonies on Sabouraud's Dextrose and Blood agar
- Grows on Sabauraud's Dextrose agar
- Common contaminants
- Treatment is with Amphotericin B
- Surgery is also an option in treatment
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- Also called phycomycosis, mucormycosis
- In horses due to Basidiobolus haptosporus
- Pythiosis in horses and dogs is similar (caused by Pythium sp.
- In warm, humid environments
- Grossly:
- Lesions on head, limbs, ventral body
- In dogs also dorsolumbar region
- Yellow, rough, necrotic tissue
- Micospocically:
- Hyphae ingranulomatou tissue
- Many eosinophils