Difference between revisions of "Category:Innate Immune System"

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=Introduction=
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|pagetitle =Innate Immune System
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|pagebody = Both the innate and adaptive immune systems use receptors to recognise foreign organisms. The innate immune system uses pattern recognition receptors which acts as an early warning system. The adaptive immune response is highly specific for each organism, as B and T cells have specialist surface immunoglobulin receptors which detect specific antigens on foreign pathogens.
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<br>The Innate immune system is the body's first barrier of defence to infection. It relies on an older, more generic, and faster acting set of tools than the [[:Category:Adaptive Immune System|adaptive]] system.  While the adaptive system is essential for a specific response to infection, it is ultimately the innate system that conquers foreign attackers through means of phagocytosis. 
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|contenttitle = Content
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|contentbody =<big><b>
  
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The Innate immune system is the body's first barrier of defence to infection. It relies on an older, more generic, and faster acting set of tools than the [[Adaptive Immune System - WikiBlood|adaptive]] system.  While the adaptive system is essential for a specific response to infection, it is ultimately the innate system that conquers foreign attackers through means of phagocytosis. 
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<categorytree mode=pages>Innate Immune System</categorytree>
  
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* Non-specific protective mechanisms include such innate factors as:
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</b></big>
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** '''Physical barriers'''
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|logo = Immature MDDC.png
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*** Skin
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*** Ciliated mucous membranes
 
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*** Commensal organisms
 
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** '''Humoral factors'''
 
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*** Lysozyme
 
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*** [[Complement|Complement]]
 
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*** Interferons
 
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** '''Cellular mechanisms'''
 
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*** Phagocytosis
 
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** Factors which regulate '''species specificity'''
 
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*** Membrane receptors for pathogens
 
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*** Nutritional requirements
 
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*** Temperature
 
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*** pH
 
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* Mechanisms of innate immunity are always present and generally unchanging
 
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* Adaptive immunity is acquired only on contact with the infectious agent (antigen) and therefore does not function before first contact with the antigen
 
  
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=Actions of the Innate Immune System=
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<br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br>
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==[[Recognition of Microorganisms]]==
 
  
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==[[Phagocytosis]]==
 
  
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=Tools of Innate Immunity=
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[[Category:Immunology|B]]
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==[[Innate Immunity Barriers]]==
 
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==[[Humoral Factors of Innate Immune System]]==
 
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==[[Innate Immunity Cellular Responses]]==
 
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=[[Innate Immunity to Viruses]]=
 
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=Innate Immunity to Bacteria=
 
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[[Image:Bacterial innate response.jpg|thumb|right|150px|Bacterial responses - B. Catchpole, RVC 2008]]
 
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The innate response to bacterial infection lies in its first-response role of detection of a foreign organism.  By using the above described tools of Pattern-Recognition Receptors (PRRs), the innate response flags up problems while the [[Adaptive Immune System - WikiBlood|adaptive]] response gets itself organized.  Once a foreign organism is detected, the innate system responds by engaging in cell warfare via phagocytosis and triggering the [[Inflammation - WikiBlood|inflammatory]] response.  The release of inflammatory [[Cytokines - WikiBlood|cytokines]] will cause an increase in vasodilation, vascular permeability and an influx of white blood cells.  Neutrophils take on their primary role as phagocytes in this phase.  In addition, systemic effects of inflammatory cytokines will sustain a rise in core temperature (fever), the release of acute phase proteins from the [[Liver - Anatomy & Physiology|liver]], and bone marrow mobilization as the need for white blood cells production is increased.  Acute phase proteins will bind to bacterial cell walls, enhancing neutrophil, macrophage, and [[Complement|complement]]-initiated phagocytosis.
 
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=[[Interplay of Innate and Adaptive Immunity - WikiBlood|Interplay of Innate and Adaptive Immunity]]=
 
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=[[Innate Immunity Flashcards|Innate Immunity Flashcards]]=
 
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=Links=
 
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'''Websites'''
 
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*http://www.cellsalive.com
 
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=References=
 
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[[Category:Immunology]]
 

Latest revision as of 06:50, 12 June 2012

Innate Immune System

Both the innate and adaptive immune systems use receptors to recognise foreign organisms. The innate immune system uses pattern recognition receptors which acts as an early warning system. The adaptive immune response is highly specific for each organism, as B and T cells have specialist surface immunoglobulin receptors which detect specific antigens on foreign pathogens.
The Innate immune system is the body's first barrier of defence to infection. It relies on an older, more generic, and faster acting set of tools than the adaptive system. While the adaptive system is essential for a specific response to infection, it is ultimately the innate system that conquers foreign attackers through means of phagocytosis.

Content

▼ Innate Immune System
  Innate Immune System - Introduction
  Humoral Factors of Innate Immune System
  Complement
  Innate Immunity Barriers
  Innate Immunity Cellular Responses
  Innate Immunity to Bacteria
  Innate Immunity to Viruses
  Phagocytosis
  Recognition of Microorganisms
  Innate Immunity Flashcards


















































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