Changes

IgA is a dimeric immunoglobulin that is produced by the joining of two IgA monomers by a ‘J’ chain. Its heavy chain is type alpha(α). There are two types of IgA:

IgA is a dimeric immunoglobulin that is produced by the joining of two IgA monomers by a ‘J’ chain. Its heavy chain is type alpha(α). There are two types of IgA:

'''Type 1''' - Non-secretory and found in blood.

:'''Type 1''' - Non-secretory and found in blood.

 

:'''Type 2''' – Secretory and secreted on mucosal surfaces.

'''Type 2''' – Secretory and secreted on mucosal surfaces.

Only Type 2 contains the secretory component, a glycoprotein, which protects IgA from digestion and mediates its active transport across mucosal epithelium. The secretory component is added to salivary IgA by mucosal epithelial cells in the salivary glands, while in the alimentary tract, the secretory component is produced by the enterocytes.

Only Type 2 contains the secretory component, a glycoprotein, which protects IgA from digestion and mediates its active transport across mucosal epithelium. The secretory component is added to salivary IgA by mucosal epithelial cells in the salivary glands, while in the alimentary tract, the secretory component is produced by the enterocytes.

[[Category:Immunoglobulins]]

[[Category:Immunoglobulins]]

[[Category:Image Review]]

[[Category:A&P Done]]

[[Category:To Do - AimeeHicks]][[Category:To Do - Review]]