Changes

**Seen in horses and dogs

**Seen in horses and dogs

**Histologically:

**Histologically:

***Central zone - proliferating undifferentiated cells and [[Chronic Inflammation - Pathology#Fibroblasts|fibroblasts]]

***Central zone - proliferating undifferentiated cells and [[Chronic Inflammation - Introduction#Fibroblasts|fibroblasts]]

***Middle zone - [[Bones - normal#Normal structure|osteoblasts]] depositing osteoid and bone

***Middle zone - [[Bones - normal#Normal structure|osteoblasts]] depositing osteoid and bone

***Outer zone - [[Bones - normal#Bone organisation|trabecular bone]] remodelled by [[Bones - normal#Normal structure|osteoclasts]]

***Outer zone - [[Bones - normal#Bone organisation|trabecular bone]] remodelled by [[Bones - normal#Normal structure|osteoclasts]]