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945 bytes added ,  13:30, 4 May 2009
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*Commonly pulmonary infections occur
 
*Commonly pulmonary infections occur
 
**Other organs can be involved
 
**Other organs can be involved
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**Involves the reticuloendothelial system
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**Intestinal form can also occur
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*Acute and chronic disease can occur
    
*Endemic to the USA
 
*Endemic to the USA
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*Respiratory infection
 
*Respiratory infection
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**Infection via ingestion can also occur
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*Affects dogs, cats, cattle, horses and humans
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*Found in soil contaminated by bird droppings, decaying vegetation and in caves inhabited by bats
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*Fine, branching, septate hyphae with smooth-walled pyriform to spherical microconidia and large, thick-walled tuberculate macroconidia on simple conidiophores
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*Dimorphic fungi
   −
*Affects dogd, cats, cattle, horses and humans
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*Hard to demonstrate in smears as the organisms is very small
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**Stain with Giemsa or Wright and examine under oil immersion lens
    
*Present intracellularly in macrophages as oval yeast cells with few buds
 
*Present intracellularly in macrophages as oval yeast cells with few buds
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**Clear halo is seen around the darker staining central material
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*Found in soil contaminated by bird droppings and in caes inhabited by bats
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*Grows on Sabouraud's Dextrose agar
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**Creamy white turning tan and then brown
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*Fine, branching, septate hyphae with smooth-walled pyriform to spherical microconidia and large, thick-walled tuberculate macroconidia on simple conidiophores
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*Also grows on Blood agar
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**Small, white yeast-like colonies
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*Test using immunodiffusion, complement fixation and counterimmunoelectrophoresis
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**Skin test of little value as it only indicates exposure
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*Treatment with [[Antifungal Drugs#Polyene Antifungals|Amphotericin B]]
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**If [[Antifungal Drugs#Polyene Antifungals|Amphotericin B]] is contra-indicated, [[Antifungal Drugs#Imidazoles|imidazoles]] can be given orally
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*THe prognosis is poor in acute and disseminated cases
    
==Zygomycosis==
 
==Zygomycosis==
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